Nutritional management of patients with acute pancreatitis: a Dutch observational multicentre study

Summary Background Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route. Aim To evaluate the nutritional management of patients with AP in a Dutch cohort (EARL study). Methods Observational study in 18 hospitals. Total days of NPO, tube feeding (TF) with/without oral feeding, total parenteral nutrition (TPN) and total starvation time were analysed. Results In mild AP, a majority of cases (80.7%, 117/145) were managed with a... Mehr ...

Verfasser: SPANIER, B. W. M.
MATHUS‐VLIEGEN, E. M. H.
TUYNMAN, H. A. R. E.
VAN DER HULST, R. W. M.
DIJKGRAAF, M. G. W.
BRUNO, M. J.
Dokumenttyp: Artikel
Erscheinungsdatum: 2008
Reihe/Periodikum: Alimentary Pharmacology & Therapeutics ; volume 28, issue 9, page 1159-1165 ; ISSN 0269-2813 1365-2036
Verlag/Hrsg.: Wiley
Schlagwörter: Pharmacology (medical) / Gastroenterology / Hepatology
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26690729
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://dx.doi.org/10.1111/j.1365-2036.2008.03814.x

Summary Background Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route. Aim To evaluate the nutritional management of patients with AP in a Dutch cohort (EARL study). Methods Observational study in 18 hospitals. Total days of NPO, tube feeding (TF) with/without oral feeding, total parenteral nutrition (TPN) and total starvation time were analysed. Results In mild AP, a majority of cases (80.7%, 117/145) were managed with an NPO regimen only. Twenty‐seven patients (18.6%) with mild AP additionally received TF; one received TPN. Of those with severe AP, more than half of the patients (56.2%, nine of 16) were treated with TF besides an NPO regimen; four received TPN. TF was delivered preferably via the jejunal route. The median period of total starvation was 2 days for both mild and severe AP. Only 5.5% (nine of 164) of patients had a prolonged starvation time of more than 5 days. Conclusions The total time of starvation was limited in a majority of patients admitted for AP. According to international guidelines, additional nutritional interventions were quickly undertaken with enteral feeding via the jejunum as the preferred route.