Inbreeding depression across the genome of Dutch Holstein Friesian dairy cattle
Abstract Background Inbreeding depression refers to the decrease in mean performance due to inbreeding. Inbreeding depression is caused by an increase in homozygosity and reduced expression of (on average) favourable dominance effects. Dominance effects and allele frequencies differ across loci, and consequently inbreeding depression is expected to differ along the genome. In this study, we investigated differences in inbreeding depression across the genome of Dutch Holstein Friesian cattle, by estimating dominance effects and effects of regions of homozygosity (ROH). Methods Genotype (75 k) a... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2020 |
Reihe/Periodikum: | Genetics Selection Evolution ; volume 52, issue 1 ; ISSN 1297-9686 |
Verlag/Hrsg.: |
Springer Science and Business Media LLC
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Schlagwörter: | Genetics / Animal Science and Zoology / General Medicine / Ecology / Evolution / Behavior and Systematics |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26689634 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1186/s12711-020-00583-1 |