Background : To investigate the association between altered sex hormone expression and long-term right ventricular (RV) adaptation and progression of right heart failure in a Dutch cohort of Pulmonary Arterial Hypertension (PAH)-patients across a wide range of ages. Methods : In this study we included 279 PAH-patients, of which 169 females and 110 males. From 59 patients and 21 controls we collected plasma samples for sex hormone analysis. Right heart catheterization (RHC) and/or cardiac magnetic resonance (CMR) imaging was performed at baseline. For longitudinal data analysis we selected pati... Mehr ...
| Verfasser: |
van Wezenbeek, Jessie
Groeneveldt, Joanne A.
Llucià-Valldeperas, Aida
van der Bruggen, Cathelijne E.
Jansen, Samara M. A.
Smits, A. Josien
Smal, Rowan
van Leeuwen, Joost W.
Remedios, Cris dos
Keogh, Anne
Humbert, Marc
Dorfmüller, Peter
Mercier, Olaf
Guignabert, Christophe
Niessen, Hans W. M.
Handoko, M. Louis
Marcus, J. Tim
Meijboom, Lilian J.
Oosterveer, Frank P. T.
Westerhof, Berend E.
Heijboer, Annemieke C.
Bogaard, Harm Jan
Noordegraaf, Anton Vonk
Goumans, Marie José
de Man, Frances S. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2022 |
| Reihe/Periodikum: |
van Wezenbeek , J , Groeneveldt , J A , Llucià-Valldeperas , A , van der Bruggen , C E , Jansen , S M A , Smits , A J , Smal , R , van Leeuwen , J W , Remedios , C D , Keogh , A , Humbert , M , Dorfmüller , P , Mercier , O , Guignabert , C , Niessen , H W M , Handoko , M L , Marcus , J T , Meijboom , L J , Oosterveer , F P T , Westerhof , B E , Heijboer , A C , Bogaard , H J , Noordegraaf , A V , Goumans , M J & de Man , F S 2022 , ' Interplay of sex hormones and long-term right ventricular adaptation in a Dutch PAH-cohort ' , Journal of Heart and Lung Transplantation , vol. 41 , no. 4 , pp. 445-457 . https://doi.org/10.1016/j.healun.2021.11.004 |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26688106 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vumc.nl/en/publications/f0f3ff9f-d328-4138-a72b-9952cfb210b4 |
