Real-world Outcomes of Sequential Androgen-receptor Targeting Therapies with or Without Interposed Life-prolonging Drugs in Metastatic Castration-resistant Prostate Cancer:Results from the Dutch Castration-resistant Prostate Cancer Registry

BACKGROUND: Cross resistance between androgen-receptor targeting therapies (ARTs) (abiraterone acetate plus prednisone [ABI+P] or enzalutamide [ENZ]) for treatment of metastatic castration-resistant prostate cancer (mCRPC) may affect responses to second ART (ART2). OBJECTIVE: To establish treatment duration and prostate-specific antigen (PSA) response of ART2 in real-world mCRPC patients treated with or without other life-prolonging drugs (LPDs; ie, docetaxel, cabazitaxel, or radium-223) between ART1 and ART2. DESIGN, SETTING, AND PARTICIPANTS: Castration-resistant prostate cancer patients, di... Mehr ...

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Verfasser: Kuppen, Malou C P
Westgeest, Hans M
van den Eertwegh, Alphonsus J M
van Moorselaar, Reindert J A
van Oort, Inge M
Coenen, Juleon L L M
van den Bergh, A C M Fons
Mehra, Niven
Somford, Diederik M
Bergman, Andre M
Ten Bokkel Huinink, Daan
Fossion, Laurent
Geenen, Maud M
Hendriks, Mathijs P
van de Luijtgaarden, Addy C M
Polee, Marco B
Weijl, Nir I
van de Wouw, Agnes J
de Wit, Ronald
Uyl-de Groot, Carin A
Gerritsen, Winald R
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: Kuppen , M C P , Westgeest , H M , van den Eertwegh , A J M , van Moorselaar , R J A , van Oort , I M , Coenen , J L L M , van den Bergh , A C M F , Mehra , N , Somford , D M , Bergman , A M , Ten Bokkel Huinink , D , Fossion , L , Geenen , M M , Hendriks , M P , van de Luijtgaarden , A C M , Polee , M B , Weijl , N I , van de Wouw , A J , de Wit , R , Uyl-de Groot , C A & Gerritsen , W R 2021 , ' Real-world Outcomes of Sequential Androgen-receptor Targeting Therapies with or Without Interposed Life-prolonging Drugs in Metastatic Castration-resistant Prostate Cancer : Results from the Dutch Castration-resistant Prostate Cancer Registry ' , European Urology Oncology , vol. 4 , no. 4 , pp. 618-627 . https://doi.org/10.1016/j.euo.2019.09.005
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26688021
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vumc.nl/en/publications/cba71d09-b119-4d6f-858e-74cf262585b6