FAM19A4/miR124-2 methylation analysis as a triage test for HPV-positive women:cross-sectional and longitudinal data from a Dutch screening cohort
OBJECTIVES: The aim was to evaluate the cross-sectional and long-term triage performance of FAM19A4/miR124-2 methylation analysis in human papillomavirus (HPV)-based cervical screening. METHODS: We conducted a post hoc analysis within a Dutch population-based HPV-positive study cohort of women aged 30-60 years (n = 979). Cross-sectional cervical intraepithelial neoplasia (CIN) 3+ sensitivity, specificity, positive predictive value and negative predictive value as well as cumulative CIN3+ or cervical cancer risks after 9 and 14 years were compared for three baseline triage strategies: (1) cytol... Mehr ...
Verfasser: |
Vink, F J
Lissenberg-Witte, B I
Meijer, C J L M
Berkhof, J
van Kemenade, F J
Siebers, A G
Steenbergen, R D M
Bleeker, M C G
Heideman, D A M |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2021 |
Reihe/Periodikum: |
Vink , F J , Lissenberg-Witte , B I , Meijer , C J L M , Berkhof , J , van Kemenade , F J , Siebers , A G , Steenbergen , R D M , Bleeker , M C G & Heideman , D A M 2021 , ' FAM19A4/miR124-2 methylation analysis as a triage test for HPV-positive women : cross-sectional and longitudinal data from a Dutch screening cohort ' , Clinical Microbiological and Infection , vol. 27 , no. 1 , pp. 125.e1-125.e6 . https://doi.org/10.1016/j.cmi.2020.03.018 |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26687740 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vumc.nl/en/publications/57cf5ede-2725-4344-85fb-7c740d3f0f93 |