The SNAP-25 gene is associated with cognitive ability: evidence from a family-based study in two independent Dutch cohorts

The synaptosomal-associated protein of 25 kDa (SNAP-25) gene plays an integral role in synaptic transmission, and is differentially expressed in the mammalian brain in the neocortex, hippocampus, anterior thalamic nuclei, substantia nigra and cerebellar granular cells. Recent studies have suggested a possible involvement of SNAP-25 in learning and memory, both of which are key components of human intelligence. In addition, the SNAP-25 gene lies in a linkage area implicated previously in human intelligence. In two independent family-based Dutch samples of 391 (mean age 12.4 years) and 276 (mean... Mehr ...

Verfasser: Gosso, M.F.
de Geus, E.J.C.
van Belzen, MJ
Polderman, T.J.C.
Heutink, P.
Boomsma, D.I.
Posthuma, D.
Dokumenttyp: Artikel
Erscheinungsdatum: 2006
Reihe/Periodikum: Gosso , M F , de Geus , E J C , van Belzen , MJ , Polderman , T J C , Heutink , P , Boomsma , D I & Posthuma , D 2006 , ' The SNAP-25 gene is associated with cognitive ability: evidence from a family-based study in two independent Dutch cohorts ' , Molecular Psychiatry , vol. 11 , no. 9 , pp. 878-886 . https://doi.org/10.1038/sj.mp.4001868
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR)
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26687552
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/ff55aca0-6740-44e1-99bb-79b7dc2d39c5