The prognostic and predictive value of Tregs and tumor immune subtypes in postmenopausal, hormone receptor-positive breast cancer patients treated with adjuvant endocrine therapy: a Dutch TEAM study analysis
Evidence exists for an immunomodulatory effect of endocrine therapy in hormone receptor-positive (HR+ve) breast cancer (BC). Therefore, the aim of this study was to define the prognostic and predictive value of tumor immune markers and the tumor immune profile in HR+ve BC, treated with different endocrine treatment regimens. 2,596 Dutch TEAM patients were treated with 5 years of adjuvant hormonal treatment, randomly assigned to different regimens: 5 years of exemestane or sequential treatment (2.5 years of tamoxifen-2.5 years of exemestane). Immunohistochemistry was performed for HLA class I,... Mehr ...
Verfasser: |
Engels, CC
Charehbili, A
van de Velde, CJH
Bastiaannet, E
Sajet, A
Putter, H
van Vliet, EA
van Vlierberghe, RLP
Smit, VTHBM
Bartlett, JMS
Seynaeve, Caroline
Liefers, GJ
Kuppen, PJK |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2015 |
Reihe/Periodikum: |
Engels , CC , Charehbili , A , van de Velde , CJH , Bastiaannet , E , Sajet , A , Putter , H , van Vliet , EA , van Vlierberghe , RLP , Smit , VTHBM , Bartlett , JMS , Seynaeve , C , Liefers , GJ & Kuppen , PJK 2015 , ' The prognostic and predictive value of Tregs and tumor immune subtypes in postmenopausal, hormone receptor-positive breast cancer patients treated with adjuvant endocrine therapy: a Dutch TEAM study analysis ' , Breast Cancer Research and Treatment , vol. 149 , no. 3 , pp. 587-596 . https://doi.org/10.1007/s10549-015-3269-7 |
Schlagwörter: |
/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ SDG 3 - Good Health and Well-being |
Sprache: |
unknown |
Permalink: |
https://search.fid-benelux.de/Record/base-26685496 |
Datenquelle: |
BASE;
Originalkatalog |
Powered By: |
BASE |
Link(s) :
|
https://pure.eur.nl/en/publications/79060abb-441e-44aa-8cfb-3e76689389a9 |