SARS-CoV-2 RNA and antibody dynamics in a Dutch household study with dense sampling frame

Abstract This study investigated the dynamics of SARS-CoV-2 infection and diagnostics in 242 household members of different ages and with different symptom severity after SARS-CoV-2 exposure early in the pandemic (March–April 2020). Households with a SARS-CoV-2 confirmed positive case and at least one child in the Netherlands were followed for 6 weeks. Naso (NP)- and oropharyngeal (OP) swabs, oral fluid and feces specimens were analyzed for SARS-CoV-2 RNA and serum for SARS-CoV-2-specific antibodies. The dynamics of the presence of viral RNA and the serological response was modeled to determin... Mehr ...

Verfasser: Han, Wanda G. H.
Swart, Arno
Bonačić Marinović., Axel
Eggink, Dirk
Reimerink, Johan
Wijsman, Lisa A.
van der Veer, Bas
van den Brink, Sharon
van den Brandt, Anne-Marie
van Tol, Sophie
Godeke, Gert-Jan
Brouwer, Fion
Hoogerwerf, Marieke
van Gageldonk-Lafeber, Arianne B.
van der Hoek, Wim
van den Hof, Susan
Meijer, Adam
Reukers, Daphne F. M.
Reusken, Chantal
Roof, Inge
Rots, Nynke
Dokumenttyp: Artikel
Erscheinungsdatum: 2022
Reihe/Periodikum: Scientific Reports ; volume 12, issue 1 ; ISSN 2045-2322
Verlag/Hrsg.: Springer Science and Business Media LLC
Schlagwörter: Multidisciplinary
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26685150
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://dx.doi.org/10.1038/s41598-022-11480-6