The role of tumour biological factors in technical anatomical resectability assessment of colorectal liver metastases following induction systemic treatment:An analysis of the Dutch CAIRO5 trial

Background: Large inter-surgeon variability exists in technical anatomical resectability assessment of colorectal cancer liver-only metastases (CRLM) following induction systemic therapy. We evaluated the role of tumour biological factors in predicting resectability and (early) recurrence after surgery for initially unresectable CRLM. Methods: 482 patients with initially unresectable CRLM from the phase 3 CAIRO5 trial were selected, with two-monthly resectability assessments by a liver expert panel. If no consensus existed among panel surgeons (i.e. same vote for (un)resectability of CRLM), co... Mehr ...

Verfasser: Bolhuis, Karen
Bond, Marinde J.G.
Van Amerongen, Martin J.
Komurcu, Aysun
Chapelle, Thiery
Dejong, Cornelis H.C.
Engelbrecht, Marc R.W.
Gerhards, Michael F.
Grünhagen, Dirk J.
van Gulik, Thomas M.
Hermans, John J.
De Jong, Koert P.
Kazemier, Geert
Klaase, Joost M.
Kok, Niels F.M.
Leclercq, Wouter K.G.
Liem, Mike S.L.
van Lienden, Krijn P.
Molenaar, I. Quintus
Neumann, Ulf P.
Patijn, Gijs A.
Rijken, Arjen M.
Ruers, Theo M.
Verhoef, Cornelis
de Wilt, Johannes H.W.
May, Anne M.
Punt, Cornelis J.A.
Swijnenburg, Rutger Jan
Dokumenttyp: Artikel
Erscheinungsdatum: 2023
Reihe/Periodikum: Bolhuis , K , Bond , M J G , Dutch Colorectal Cancer Group Liver Expert Panel , Van Amerongen , M J , Komurcu , A , Chapelle , T , Dejong , C H C , Engelbrecht , M R W , Gerhards , M F , Grünhagen , D J , van Gulik , T M , Hermans , J J , De Jong , K P , Kazemier , G , Klaase , J M , Kok , N F M , Leclercq , W K G , Liem , M S L , van Lienden , K P , Molenaar , I Q , Neumann , U P , Patijn , G A , Rijken , A M , Ruers , T M , Verhoef , C , de Wilt , J H W , May , A M , Punt , C J A & Swijnenburg , R J 2023 , ' The role of tumour biological factors in technical anatomical resectability assessment of colorectal liver metastases following induction systemic treatment : An analysis of the Dutch CAIRO5 trial ' , European Journal of Cancer , vol. 183 , pp. 49-59 . https://doi.org/10.1016/j.ejca.2023.01.013
Schlagwörter: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26684212
Datenquelle: BASE; Originalkatalog
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Link(s) : https://pure.eur.nl/en/publications/54121785-1991-4fc9-b920-197b8ab0085a