Prognostic factors and survival in MEN1 patients with gastrinomas : Results from the DutchMEN study group (DMSG)
BACKGROUND AND OBJECTIVES: Gastrinomas are the most prevalent functioning neuroendocrine tumors (NET) in multiple endocrine neoplasia type 1 (MEN1). Guidelines suggest medical therapy in most patients, but surgery may be considered in a subgroup. Currently, factors to guide management are necessary. This population-based cohort study assessed prognostic factors of survival in patients with MEN1-related gastrinomas. METHODS: Patients with MEN1 having gastrinomas were identified in the Dutch MEN1 database from 1990 to 2014 based on fasting serum gastrin (FSG) levels and/or pathology. Predictors... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2019 |
Schlagwörter: | Zollinger-Ellison syndrome / multiple endocrine neoplasia type 1 / neuroendocrine tumor / oncology / Prognosis / Follow-Up Studies / Intestinal Neoplasms/metabolism / Gastrinoma/metabolism / Humans / Middle Aged / Neuroendocrine Tumors/metabolism / Proto-Oncogene Proteins/metabolism / Male / Survival Rate / Pancreatic Neoplasms/metabolism / Stomach Neoplasms/metabolism / Netherlands / Female / Cohort Studies / Liver Neoplasms/metabolism / Surgery / Journal Article |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26681525 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/391581 |