Trial by Dutch laboratories for evaluation of non-invasive prenatal testing. Part I—clinical impact
Objective: To evaluate the clinical impact of nationwide implementation of genome-wide non-invasive prenatal testing (NIPT) in pregnancies at increased risk for fetal trisomies 21, 18 and 13 (TRIDENT study). Method: Women with elevated risk based on first trimester combined testing (FCT ≥ 1:200) or medical history, not advanced maternal age alone, were offered NIPT as contingent screening test, performed by Dutch University Medical laboratories. We analyzed uptake, test performance, redraw/failure rate, turn-around time and pregnancy outcome. Results: Between 1 April and 1 September 2014, 1413... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2016 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26678019 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://repub.eur.nl/pub/94873 |