The Dutch hypertension and offspring study : an epidemiological approach to the early pathogenesis of primary hypertension

Mechanisms to explain chronic elevation of blood pressure, hypertension, have been much debated and reviewed. The development ideas can be traced back to the early 19th century, in observations by Bright of an association between high blood pressure and albuminuria. In the more recent past attention has shifted to the cardiovascular consequences of elevated blood pressure, This association has repeatedly been confirmed and is well quantified by epidemio'iogists in large longitudinal observational studies, as summarized in several metaM analyses. Although age standardized mortality rates from c... Mehr ...