Outbreak of NDM-1-Producing Klebsiella pneumoniae in a Dutch Hospital, with Interspecies Transfer of the Resistance Plasmid and Unexpected Occurrence in Unrelated Health Care Centers
In the Netherlands, the number of cases of infection with New Delhi metallo-beta-lactamase (NDM)-positive Enterobacteriaceae is low. Here, we report an outbreak of NDM-1-producing Klebsiella pneumoniae infection in a Dutch hospital with interspecies transfer of the resistance plasmid and unexpected occurrence in other unrelated health care centers (HCCs). Next-generation sequencing was performed on 250 carbapenemase-producing Enterobacteriaceae isolates, including 42 NDM-positive isolates obtained from 29 persons at the outbreak site. Most outbreak isolates were K. pneumoniae (n = 26) and Esch... Mehr ...
Verfasser: |
Bosch, Thijs
Lutgens, Suzanne P M
Hermans, Mirjam H A
Wever, Peter C
Schneeberger, Peter M.
Renders, Nicole H M
Leenders, Alexander C. A. P.
Kluytmans, Jan A. J. W.
Schoffelen, Annelot F
Notermans, Daan
Witteveen, Sandra
Bathoorn, Erik
Schouls, Leo M. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2017 |
Reihe/Periodikum: |
Bosch , T , Lutgens , S P M , Hermans , M H A , Wever , P C , Schneeberger , P M , Renders , N H M , Leenders , A C A P , Kluytmans , J A J W , Schoffelen , A F , Notermans , D , Witteveen , S , Bathoorn , E & Schouls , L M 2017 , ' Outbreak of NDM-1-Producing Klebsiella pneumoniae in a Dutch Hospital, with Interspecies Transfer of the Resistance Plasmid and Unexpected Occurrence in Unrelated Health Care Centers ' , Journal of Clinical Microbiology , vol. 55 , no. 8 , pp. 2380-2390 . https://doi.org/10.1128/JCM.00535-17 |
Schlagwörter: |
Klebsiella
/ NDM
/ carbapenems
/ outbreak
/ METALLO-BETA-LACTAMASE
/ ANTIBIOTIC-RESISTANCE
/ ESCHERICHIA-COLI
/ EMERGENCE
/ SPREAD
/ HUMANS
/ GENES |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26672138 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://hdl.handle.net/11370/f0a0c6fd-6a39-4e5b-bf87-8a88b76f8c0a |