Genetic Evaluation of A Nation-Wide Dutch Pediatric DCM Cohort:The Use of Genetic Testing in Risk Stratification
BACKGROUND: This study aimed to describe the current practice and results of genetic evaluation in Dutch children with dilated cardiomyopathy and to evaluate genotype-phenotype correlations that may guide prognosis. METHODS: We performed a multicenter observational study in children diagnosed with dilated cardiomyopathy, from 2010 to 2017. RESULTS: One hundred forty-four children were included. Initial diagnostic categories were idiopathic dilated cardiomyopathy in 67 children (47%), myocarditis in 23 (16%), neuromuscular in 7 (5%), familial in 18 (13%), inborn error of metabolism in 4 (3%), m... Mehr ...
| Verfasser: |
van der Meulen, Marijke H.
Herkert, Johanna C.
den Boer, Susanna L.
du Marchie Sarvaas, Gideon J.
Blom, Nico A.
Ten Harkel, Arend D.J.
Breur, Hans M.P.J.
Rammeloo, Lukas A.J.
Tanke, Ronald B.
Marcelis, Carlo
van de Laar, Ingrid M.B.H.
Verhagen, Judith M.A.
Lekanne Dit Deprez, Ronald H.
Barge-Schaapveld, Daniela Q.C.M.
Baas, Annette F.
Sammani, Arjan
Christiaans, Imke
van Tintelen, J. Peter
Dalinghaus, Michiel |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2022 |
| Reihe/Periodikum: |
van der Meulen , M H , Herkert , J C , den Boer , S L , du Marchie Sarvaas , G J , Blom , N A , Ten Harkel , A D J , Breur , H M P J , Rammeloo , L A J , Tanke , R B , Marcelis , C , van de Laar , I M B H , Verhagen , J M A , Lekanne Dit Deprez , R H , Barge-Schaapveld , D Q C M , Baas , A F , Sammani , A , Christiaans , I , van Tintelen , J P & Dalinghaus , M 2022 , ' Genetic Evaluation of A Nation-Wide Dutch Pediatric DCM Cohort : The Use of Genetic Testing in Risk Stratification ' , Circulation. Genomic and precision medicine , vol. 15 , no. 5 , e002981 . https://doi.org/10.1161/CIRCGEN.120.002981 |
| Schlagwörter: |
cardiomyopathy
/ dilated
/ genetic testing
/ pediatric cardiology |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26671509 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/a9e1bc42-55c3-45fb-b1dc-1c5992d89df7 |
