Outcomes for systemic therapy in older patients with metastatic melanoma:Results from the Dutch Melanoma Treatment Registry
BACKGROUND: The incidence of metastatic melanoma is increasing in all ages. Multiple trials with targeted drugs and immune checkpoint inhibitors showed improved survival in metastatic melanoma. However, patients aged ≥75 years are often under-represented in clinical trials, therefore raising questions on safety and efficacy of treatment. PATIENTS AND METHODS: We analyzed a real-world cohort of 3054 patients with metastatic melanoma stratified for age (≤65 years, 66-74 years and ≥ 75 years), and BRAF status, providing data on treatment strategies, toxicity, and survival. Kaplan Meier curves and... Mehr ...
Verfasser: |
Jochems, Anouk
Bastiaannet, Esther
Aarts, Maureen J B
van Akkooi, Alexander C J
van den Berkmortel, Franchette W P J
Boers-Sonderen, Marye J
van den Eertwegh, Alfonsus J M
de Glas, Nienke G
de Groot, Jan Willem B
Haanen, John B A G
Hospers, Geke A P
van der Hoeven, Jacobus J M
Piersma, Djura
van Rijn, Rozemarijn S
Suijkerbuijk, Karijn P M
Ten Tije, Albert J
van der Veldt, Astrid A M
Vreugdenhil, Gerard
van Zeijl, Michiel C T
Kapiteijn, Ellen
Wouters, Michel W J M |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2021 |
Reihe/Periodikum: |
Jochems , A , Bastiaannet , E , Aarts , M J B , van Akkooi , A C J , van den Berkmortel , F W P J , Boers-Sonderen , M J , van den Eertwegh , A J M , de Glas , N G , de Groot , J W B , Haanen , J B A G , Hospers , G A P , van der Hoeven , J J M , Piersma , D , van Rijn , R S , Suijkerbuijk , K P M , Ten Tije , A J , van der Veldt , A A M , Vreugdenhil , G , van Zeijl , M C T , Kapiteijn , E & Wouters , M W J M 2021 , ' Outcomes for systemic therapy in older patients with metastatic melanoma : Results from the Dutch Melanoma Treatment Registry ' , Journal of Geriatric Oncology , vol. 12 , no. 7 , pp. 1031-1038 . https://doi.org/10.1016/j.jgo.2021.04.006 |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26670513 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://hdl.handle.net/11370/31c18c4b-2ad6-4933-b220-6112d74cad77 |