Extracolonic cancer risk in Dutch patients with APC (adenomatous polyposis coli)-associated polyposis
Background: Screening of patients with familial adenomatous polyposis (FAP) have led to a substantial reduction in mortality due to colorectal cancer (CRC). Recent guidelines suggest that surveillance of nonintestinal malignancies should also be considered in those patients. However, the value of these surveillance programmes is unknown. The aims of this study were (1) to assess the occurrence of extracolonic malignancies in a large series of adenomatous polyposis coli (APC) mutation carriers and (2) to evaluate the causes of death. Methods: All APC mutation carriers were selected from the Dut... Mehr ...
Verfasser: |
Ghorbanoghli, Zeinab
Bastiaansen, Barbara A. J.
Langers, Alexandra M. J.
Nagengast, Fokko M.
Poley, Jan-Werner
Hardwick, James C. H.
Koornstra, Jan J.
Sanduleanu, Silvia
Cappel, Wouter H. de Vos tot Nederveen
Witteman, Ben J. M.
Morreau, H.
Dekker, Evelien
Vasen, Hans F. A. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2018 |
Reihe/Periodikum: |
Ghorbanoghli , Z , Bastiaansen , B A J , Langers , A M J , Nagengast , F M , Poley , J-W , Hardwick , J C H , Koornstra , J J , Sanduleanu , S , Cappel , W H D V T N , Witteman , B J M , Morreau , H , Dekker , E & Vasen , H F A 2018 , ' Extracolonic cancer risk in Dutch patients with APC (adenomatous polyposis coli)-associated polyposis ' , Journal of Medical Genetics , vol. 55 , no. 1 , pp. 11-14 . https://doi.org/10.1136/jmedgenet-2017-104545 |
Schlagwörter: |
FAMILIAL ADENOMATOUS POLYPOSIS
/ DUODENAL ADENOMATOSIS
/ REGISTRATION
/ NETHERLANDS
/ PREVALENCE
/ MANAGEMENT
/ CARCINOMA
/ GENE |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26670372 |
Datenquelle: |
BASE;
Originalkatalog |
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BASE |
Link(s) :
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https://hdl.handle.net/11370/1f622b12-9f3a-4b52-8720-da3f8b72a7f0 |