Poster Design SysPharmPediA study (presented at Dutch Lung Days - 2017)

Childhood asthma is a complex multifactorial disease usually treated with inhaled corticosteroids (ICS) as controller medication. However, large variability in treatment response to, ICS is observed. A uniform, integrated systems pharmacology approach is needed to disentangle the complexity of the disease and identify phenotypes that are predictive of therapy response. This study aims: •To identify genetic and non-genetic biomarkers to characterize phenotypes of non-response to standard asthma therapy with ICS •To construct computational algorithms that effectively predict phenotype of ICS res... Mehr ...