Impact of analysis of the sentinel lymph node by one-step nucleic acid amplification (OSNA) compared to conventional histopathology on axillary and systemic treatment:data from the Dutch nationwide cohort of breast cancer patients
PurposeThe outcome of the sentinel lymph node in breast cancer patients affects adjuvant treatment. Compared to conventional histopathology, analysis by one-step nucleic acid amplification (OSNA) harvests more micrometastasis, potentially inducing overtreatment. In this study we investigated the impact of OSNA analysis on adjuvant treatment, compared to histopathological analysis.MethodsData from T1-3 breast cancer patients with sentinel nodes analysed between January 2016 and December 2019 by OSNA (OSNA group, n = 1086) from Zuyderland Medical Centre, the Netherlands, were compared to concurr... Mehr ...
| Verfasser: |
van Haaren, Elisabeth R. M.
Poodt, Ingrid G. M.
van Weezelenburg, Merel Spiekerman A.
van Bastelaar, James
Janssen, Alfred
de Vries, Bart
Lobbes, Marc B. I.
Bouwman, Lee H.
Vissers, Yvonne L. J. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2023 |
| Reihe/Periodikum: |
van Haaren , E R M , Poodt , I G M , van Weezelenburg , M S A , van Bastelaar , J , Janssen , A , de Vries , B , Lobbes , M B I , Bouwman , L H & Vissers , Y L J 2023 , ' Impact of analysis of the sentinel lymph node by one-step nucleic acid amplification (OSNA) compared to conventional histopathology on axillary and systemic treatment : data from the Dutch nationwide cohort of breast cancer patients ' , Breast Cancer Research and Treatment , vol. 202 , no. 2 , pp. 245-255 . https://doi.org/10.1007/s10549-023-07065-0 |
| Schlagwörter: |
Breast cancer
/ Sentinel lymph node biopsy
/ One-step nucleic acid amplification
/ Adjuvant treatment
/ METASTASIS
/ DISSECTION
/ BIOPSY
/ TRIAL
/ MICROMETASTASIS
/ UNDERTREATMENT
/ MULTICENTER
/ ONCOLOGY
/ WOMEN
/ AGE |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26664684 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://cris.maastrichtuniversity.nl/en/publications/e02ce54d-b38d-4c1c-8d05-0790f8bd02f0 |
