Treatment and outcome of the Dutch Childhood Craniopharyngioma Cohort study: First results after centralization of care

Abstract Background Childhood craniopharyngioma (cCP) has excellent survival, but quality of life may be severely hampered by hypothalamic dysfunction. We aimed to evaluate treatment and hypothalamic outcomes of a Dutch cCP cohort, and evaluate the effect of centralization of care. Methods A retrospective cohort study was performed, including cCP patients diagnosed between 2004 and 2021. Treatment characteristics and hypothalamic outcomes were evaluated and compared before and since centralization of care in May 2018. Results We included 87 cCP patients. Cyst drainage/fenestration was performe... Mehr ...