Applying Risk-Based Follow-Up Strategies on the Dutch Breast Cancer Population:Consequences for Care and Costs

Objectives: An important aim of follow-up after primary breast cancer treatment is early detection of locoregional recurrences (LRR). This study compares 2 personalized follow-up scheme simulations based on LRR risk predictions provided by a time dependent prognostic model for breast cancer LRR and quantifies their possible follow-up efficiency. Methods: Surgically treated early patients with breast cancer between 2003 and 2008 were selected from the Netherlands Cancer Registry. The INFLUENCE nomogram was used to estimate the 5-year annual LRR. Applying 2 thresholds, they were defined accordin... Mehr ...