Short-Term Outcomes of Secondary Liver Surgery for Initially Unresectable Colorectal Liver Metastases Following Modern Induction Systemic Therapy in the Dutch CAIRO5 Trial

Objective: To present short-term outcomes of liver surgery in patients with initially unresectable colorectal liver metastases (CRLM) downsized by chemotherapy plus targeted agents. Background: The increase of complex hepatic resections of CRLM, technical innovations pushing boundaries of respectability, and use of intensified induction systemic regimens warrant for safety data in a homogeneous multicenter prospective cohort. Methods: Patients with initially unresectable CRLM, who underwent complete resection after induction systemic regimens with doublet or triplet chemotherapy, both plus tar... Mehr ...

Verfasser: Bolhuis, K.
Grosheide, L.
Wesdorp, N.J.
Komurcu, A.
Chapelle, T.
Dejong, C.H.C.
Gerhards, M.F.
Grunhagen, D.J.
van Gulik, T.M.
Huiskens, J.
De Jong, K.P.
Kazemier, G.
Klaase, J.M.
Liem, M.S.L.
Molenaar, I.Q.
Patijn, G.A.
Rijken, A.M.
Ruers, T.M.
Verhoef, C.
de Wilt, J.H.W.
Punt, C.J.A.
Swijnenburg, R.J.
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: Bolhuis , K , Grosheide , L , Wesdorp , N J , Komurcu , A , Chapelle , T , Dejong , C H C , Gerhards , M F , Grunhagen , D J , van Gulik , T M , Huiskens , J , De Jong , K P , Kazemier , G , Klaase , J M , Liem , M S L , Molenaar , I Q , Patijn , G A , Rijken , A M , Ruers , T M , Verhoef , C , de Wilt , J H W , Punt , C J A & Swijnenburg , R J 2021 , ' Short-Term Outcomes of Secondary Liver Surgery for Initially Unresectable Colorectal Liver Metastases Following Modern Induction Systemic Therapy in the Dutch CAIRO5 Trial ' , Annals of Surgery , vol. 2 , no. 3 , e081 . https://doi.org/10.1097/AS9.0000000000000081
Schlagwörter: ablation / colorectal cancer / colorectal liver metastases / mortality / postoperative morbidity / resection / surgery / SINUSOIDAL OBSTRUCTION SYNDROME / PORTAL-VEIN EMBOLIZATION / PREOPERATIVE CHEMOTHERAPY / 2-STAGE HEPATECTOMY / HEPATIC RESECTION / POSTOPERATIVE COMPLICATIONS / CANCER / BEVACIZUMAB / OXALIPLATIN / INJURY
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26663912
Datenquelle: BASE; Originalkatalog
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Link(s) : https://cris.maastrichtuniversity.nl/en/publications/1ed551bf-2086-44a0-b46e-7b73166a6c9e