Prolonged carriage and potential onward transmission of carbapenemase-producing Enterobacteriaceae in Dutch travelers

Aim: The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. Materials & methods: Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. Results: Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strai... Mehr ...

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Verfasser: van Hattem, Jarne M.
Arcilla, Maris S.
Bootsma, Martin C. J.
van Genderen, Perry J.
Goorhuis, Abraham
Grobusch, Martin P.
Molhoek, Nicky
Oude Lashof, Astrid
Schultsz, Constance
Stobberingh, Ellen E.
Verbrugh, Henri A.
de Jong, Menno D.
Melles, Damian C.
Penders, John
Dokumenttyp: Artikel
Erscheinungsdatum: 2016
Reihe/Periodikum: van Hattem , J M , Arcilla , M S , Bootsma , M C J , van Genderen , P J , Goorhuis , A , Grobusch , M P , Molhoek , N , Oude Lashof , A , Schultsz , C , Stobberingh , E E , Verbrugh , H A , de Jong , M D , Melles , D C & Penders , J 2016 , ' Prolonged carriage and potential onward transmission of carbapenemase-producing Enterobacteriaceae in Dutch travelers ' , Future Microbiology , vol. 11 , no. 7 , pp. 857-864 . https://doi.org/10.2217/fmb.16.18
Schlagwörter: Enterobacteriaceae / carbapenemases / transmission / travel
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26663879
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://cris.maastrichtuniversity.nl/en/publications/141049a6-761f-49f1-9937-8987d2585259

Aim: The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. Materials & methods: Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. Results: Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strain, suggesting clonal transmission within this household. Conclusion: Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel.