Thrombolysis for acute stroke with special emphasis on the very old: experience from a single Dutch centre

The aim of this study was to describe the clinical experience in 184 consecutive stroke patients first-ever treated with recombinant tissue plasminogen activator (rt-PA) at a single Dutch centre, with special emphasis on results among the very old. Outcome parameters were the modified Rankin scale (mRs) at 3 months and symptomatic intracranial haemorrhage (SICH). Outcome was related to age. A total of 184 patients were treated of whom 45 were 80 years of age or older (24%). Sixty two (45%) of 139 patients <80 years of age and 12 (27%) of 45 patients ⩾80 years of age had a favourable outcome... Mehr ...