Autosomal recessive inheritance of goiter in Dutch goats
The inheritance of congenital goiter due to a thyroglobulin synthesis defect in a strain of Dutch goats has been studied by Mendelian and biochemical methods. Mendelian analysis of 301 matings, resulting in 591 kids, showed an autosomal recessive mode of inheritance. A restriction fragment length polymorphism (RFLP) in the thyroglobulin gene also was used to confirm the recessive mode of inheritance of the defect. In a pedigree consisting of 27 goats, spanning four generations, the genotype determined by RFLP study was in accordance with the observed phenotype and the autosomal inheritance of... Mehr ...
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Dokumenttyp: | TEXT |
Erscheinungsdatum: | 1987 |
Verlag/Hrsg.: |
Oxford University Press
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Schlagwörter: | Articles |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26632933 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://jhered.oxfordjournals.org/cgi/content/short/78/5/298 |