Hypokinesia and presenile dementia in a Dutch family with a novel insertion in the prion protein gene
The clinical features and disease course of six patients from a family with autosomal dominant inheritance of presenile dementia and a hypokinetic syndrome are described. In the past, these patients have carried diagnoses of Pick's disease, Huntington's disease, Parkinson—dementia, and one patient was described as suffering from a ‘peculiar type of presenile dementia’ in a case report. In the two cases examined, the most distinctive neuropathological features were extensive globular deposits of periodic acid-Schiff plus diastase (PAS)positive material, having tinctural properties of amyloid on... Mehr ...
Verfasser: | |
---|---|
Dokumenttyp: | TEXT |
Erscheinungsdatum: | 1995 |
Verlag/Hrsg.: |
Oxford University Press
|
Schlagwörter: | Articles |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26632323 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://brain.oxfordjournals.org/cgi/content/short/118/6/1565 |