A cohort study to evaluate infection prevention protocol in pediatric trauma patients with blunt splenic injury in a Dutch level 1 trauma center

Roy Spijkerman, Michel PJ Teuben, Falco Hietbrink, William LM Kramer, Luke PH Leenen Department of Surgery, University Medical Centre Utrecht, Utrecht, the Netherlands Purpose: Asplenic patients are at increased risk for the development of overwhelming postsplenectomy infection (OPSI) syndrome. It is believed that adequate immunization, antimicrobial prophylaxis, as well as appropriate education concerning risks on severe infection lead to the decreased incidence of OPSI. The aim of this study was to analyze the methods used to prevent OPSI in trauma patients splenectomized before the age of 1... Mehr ...