Consequences of a recent past dengue infection for acute and long-term chikungunya outcome:A retrospective cohort study in Curacao

Background: Dengue and chikungunya co-infections are an emerging threat to public health in tropical and subtropical areas. This study investigates acute and long-term clinical presentation patterns of chikungunya against a backdrop of preceding dengue infection and determines predicting factors for long-term chikungunya sequelae. Methods: A retrospective cohort study was performed in 2015, including 299 previously confirmed chikungunya cases, of which 162 subjects were assessed for dengue serology at disease onset. Results: Those with previous dengue infection (35.2% of the examined populatio... Mehr ...