Thermal processes represent a significant fraction of industrial energy consumptions, and they rely mainly on fossil fuels. Thanks to technological innovation, highly efficient devices such as high-temperature heat pumps are becoming a promising solution for the electrification of industrial heat. These technologies allow for recovering waste heat sources and upgrading them at temperatures up to 200 °C. Moreover, the coupling of these devices with thermal storage units can unlock the flexibility potential deriving from the industrial sector electrification by means of Demand-Side Management strategies. The aim of this paper is to quantify the impact on the energy system due to the integration of industrial high-temperature heat pumps and thermal storage units by means of a detailed demand–supply model. To do that, the industrial heat demand is investigated through a set of thermal process archetypes. High-temperature heat pumps and thermal storage units for industrial use are included in the open-source unit commitment and optimal dispatch model Dispa-SET used for the representation of the energy system. The case study analyzed is Belgium, and the analysis is performed for different renewable penetration scenarios in 2040 and 2050. The results demonstrate the importance of a proper sizing of the heat pump and thermal storage capacity. Furthermore, it is obtained that the electrification of the thermal demand of industrial processes improves the environmental impact (84% reduction in CO 2 emissions), but the positive effect of the energy flexibility provided by the heat pumps is appreciated only in the presence of a very high penetration of renewable energy sources.