Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

In Belgium, decreasing macrolide, lincosamide, streptogramins B, and tetracycline use during 1997–2007 correlated significantly with decreasing macrolide-resistant Streptococcus pyogenes during 1999–2009. Maintaining drug use below a critical threshold corresponded with low-level macrolide-resistant S. pyogenes and an increased number of erm(A)-harboring emm77 S. pyogenes with low fitness costs.

Verfasser: Liesbet Van Heirstraeten
Samuel Coenen
Christine Lammens
Niel Hens
Herman Goossens
Surbhi Malhotra-Kumar
Dokumenttyp: Artikel
Erscheinungsdatum: 2012
Reihe/Periodikum: Emerging Infectious Diseases, Vol 18, Iss 9, Pp 1515-1518 (2012)
Verlag/Hrsg.: Centers for Disease Control and Prevention
Schlagwörter: Group A streptococcus / antibiotic resistance / fitness costs / macrolide use / macrolides / erm(A) / Medicine / R / Infectious and parasitic diseases / RC109-216
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26612561
Datenquelle: BASE; Originalkatalog
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Link(s) : https://doi.org/10.3201/eid1809.120049