SARS-CoV-2 infection in captive hippos (Hippopotamus amphibius), Belgium

Abstract: Simple Summary We report the first world case of SARS-CoV-2 in captive hippos. Two adult animals were naturally infected in November 2021. Both had snot for a few days but did not need treatment. The virus was found in their noses, faeces and pool water. Antibodies were also found in the bloodstream. Two adult female hippos in Zoo Antwerp who were naturally infected with SARS-CoV-2 showed nasal discharge for a few days. Virus was detected by immunocytochemistry and PCR in nasal swab samples and by PCR in faeces and pool water. Serology was also positive. No treatment was necessary.