Use of antibiotics and colorectal cancer risk: a primary care nested case–control study in Belgium

Objectives To examine the association between the use of oral antibiotics and subsequent colorectal cancer risk. Design Matched case–control study. Setting General practice centres participating in the Integrated Computerised Network database in Flanders, Belgium. Participants In total, 1705 cases of colorectal cancer diagnosed between 01 January 2010 and 31 December 2015 were matched to 6749 controls by age, sex, comorbidity and general practice centre. Primary outcome measure The association between the number of prescriptions for oral antibiotics and the incidence of colorectal cancer over... Mehr ...