Iron Overload in Polytransfused Patients without Heart Failure is Associated with Subclinical Alterations of Systolic Left Ventricular Function using Cardiovascular Magnetic Resonance Tagging.
ABSTRACT: BACKGROUND: It remains incompletely understood whether patients with transfusion related cardiac iron overload without signs of heart failure exhibit already subclinical alterations of systolic left ventricular (LV) dysfunction. Therefore we performed a comprehensive evaluation of systolic and diastolic cardiac function in such patients using tagged and phase-contrast CMR. METHODS: 19 patients requiring regular blood transfusions for chronic anemia and 8 healthy volunteers were investigated using cine, tagged, and phase-contrast and T2* CMR. LV ejection fraction, peak filling rate, e... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2011 |
Schlagwörter: | Young Adult / Ventricular Function / Left / Ventricular Dysfunction / Torsion / Mechanical / Systole / Stroke Volume / Prospective Studies / Predictive Value of Tests / Male / Magnetic Resonance Imaging / Cine / Iron Overload / Iron Chelating Agents / Humans / Female / Diastole / Child / Case-Control Studies / Blood Transfusion / Belgium / Asymptomatic Diseases / Anemia / Analysis of Variance / Adult / Adolescent |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26573261 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/2078.1/73918 |