Analysis of differences in preventive measures after high-dose cyclophosphamide among Belgian stem cell transplant centres

Objectives: Cyclophosphamide is used in high dose in the conditioning regimen of allogeneic and autologous stem cell transplantation and early post-transplant as prophylaxis of graft-versus-host disease (GVHD). The risk of bladder toxicity and hemorrhagic cystitis is well established. However, preventive measures differ depending on local protocol.Methods: We conducted a survey among Belgian transplant centres to identify differences in preventive measures after high dose cyclophosphamide. All 15 JACIE accredited Belgian transplant centres were asked to complete a short questionnaire. Centres... Mehr ...