A dose adjustment in patients with rheumatoid arthritis not optimally responding to a standard dose of infliximab of 3 mg/kg every 8 weeks can be effective: a Belgian prospective study
Objectives . To analyse the effect of a dose increase in patients with severe rheumatoid arthritis (RA) with insufficient clinical response to 3 mg/kg infliximab every 8 weeks. Methods . Patients suffering from active refractory RA despite methotrexate, were treated with i.v. infusions of infliximab (3 mg/kg) on week 0, 2, 6 and every 8 weeks thereafter. Based on the clinical judgement at week 22, patients received a dose increase of 100 mg from week 30 on. The American College of Rheumatology (ACR) core set for disease activity measures was regularly assessed. Results . Five hundred and eleve... Mehr ...
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Dokumenttyp: | TEXT |
Erscheinungsdatum: | 2005 |
Verlag/Hrsg.: |
Oxford University Press
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Schlagwörter: | Concise report |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26533473 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://rheumatology.oxfordjournals.org/cgi/content/short/keh494v1 |