Trends and Predictors of Transmitted Drug Resistance (TDR) and Clusters with TDR in a Local Belgian HIV-1 Epidemic

We aimed to study epidemic trends and predictors for transmitted drug resistance (TDR) in our region, its clinical impact and its association with transmission clusters. We included 778 patients from the AIDS Reference Center in Leuven (Belgium) diagnosed from 1998 to 2012. Resistance testing was performed using population-based sequencing and TDR was estimated using the WHO-2009 surveillance list. Phylogenetic analysis was performed using maximum likelihood and Bayesian techniques. The cohort was predominantly Belgian (58.4%), men who have sex with men (MSM) (42.8%), and chronically infected... Mehr ...

Verfasser: Pineda-Pena, AC
Schrooten, Y
Vinken, L
Ferreira, F
Li, GD
Trovao, NS
Khouri, R
Derdelinckx, I
De Munter, P
Kucherer, C
Kostrikis, LG
Nielsen, C
Littsola, K
Wensing, A
Stanojevic, M
Paredes, R
Balotta, C
Albert, J (Jan)
Boucher, Charles
Gomez-Lopez, A
van Wijngaerden, E
van Ranst, M
Vercauteren, J
Vandamme, AM
Van Laethem, K
Dokumenttyp: Artikel
Erscheinungsdatum: 2014
Reihe/Periodikum: Pineda-Pena , AC , Schrooten , Y , Vinken , L , Ferreira , F , Li , GD , Trovao , NS , Khouri , R , Derdelinckx , I , De Munter , P , Kucherer , C , Kostrikis , LG , Nielsen , C , Littsola , K , Wensing , A , Stanojevic , M , Paredes , R , Balotta , C , Albert , J , Boucher , C , Gomez-Lopez , A , van Wijngaerden , E , van Ranst , M , Vercauteren , J , Vandamme , AM & Van Laethem , K 2014 , ' Trends and Predictors of Transmitted Drug Resistance (TDR) and Clusters with TDR in a Local Belgian HIV-1 Epidemic ' , PLoS One (print) , vol. 9 , no. 7 . https://doi.org/10.1371/journal.pone.0101738
Schlagwörter: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / SDG 3 - Good Health and Well-being
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-26530990
Datenquelle: BASE; Originalkatalog
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Link(s) : https://pure.eur.nl/en/publications/7374e40d-c366-463b-b2d5-6f3ed607ce0e