Hemophagocytic Lymphohistiocytosis in Adults: A Retrospective Study in a Belgian Teaching Hospital.

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease, which can be primary (due to genetic mutation) or secondary to malignancy, infection and rheumatologic diseases. Data concerning Belgian patients with adult HLH are lacking. This retrospective study was performed in a teaching hospital in Belgium. All cases of adult HLH, from December 2010 to April 2022, were reviewed. Patients with more than five HLH-2004 criteria and/or HScore >80% were included in the study. The objective of our study was to describe clinical and biological characteristics of patients with HLH and at... Mehr ...

Verfasser: Yildiz, Halil
Castanares Zapatero, Diego
D'Abadie, Philippe
Bailly, Sarah
Yombi, Jean Cyr
Dokumenttyp: Artikel
Erscheinungsdatum: 2022
Verlag/Hrsg.: Dove Medical Press
Schlagwörter: autoimmune disease / corticosteroid / hemophagocytic lymphohistiocytosis / infection / macrophage activation syndrome / malignancy / mortality / ruxolitinib / tocilizumab
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26530140
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://hdl.handle.net/2078.1/268710