Allele and genotype frequencies of the SOD1 gene polymorphism associated with canine degenerative myelopathy in Belgian Malinois dogs in Greece
Background and Aim: Canine degenerative myelopathy (CDM) is an adult-onset fatal disorder associated with a point mutation of the superoxide dismutase 1 (SOD1) gene (SOD1:c.118G>A). This study aimed to determine the allele and genotype frequencies of this mutation in a group of Belgian Malinois dogs in Greece. Materials and Methods: Samples (n=72) of whole blood were collected from 72 purebred dogs of the Hellenic Armed Forces; these samples were processed for DNA isolation, polymerase chain reaction, and digestion with the restriction endonuclease AcuI. Sample testing was conducted in comp... Mehr ...
Verfasser: | |
---|---|
Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2021 |
Reihe/Periodikum: | Veterinary World, Vol 14, Iss 6, Pp 1472-1479 (2021) |
Verlag/Hrsg.: |
Veterinary World
|
Schlagwörter: | degenerative myelopathy / dogs / genetic analysis / genetic polymorphism / restriction fragment length polymorphism-polymerase chain reaction / sod1:c.118a / Animal culture / SF1-1100 / Veterinary medicine / SF600-1100 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26526200 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://doi.org/10.14202/vetworld.2021.1472-1479 |