Intravenous infection of chickens with Belgian H3N1 isolates: Clinical course, HI-titers, and virus antigen detection.

Chicken were infected intravenously (i.v.) with either (A) CK/DE/1940/19 or (B) DK/BE/1358/19 H3N1 isolate. The clinical status was monitored over a period of ten days post inoculation (dpi). Clinical status is recorded as healthy (0), birds showing slight (1) or severe disturbances of the general condition (2). In both groups, one animal showed neurological signs including torticollis and was euthanized, as indicated with asterisk. Subsequently they were recorded as dead (3). The IVPI is the mean score per bird per observation over the 10-day period (1 observation per bird per day). In additi... Mehr ...

Verfasser: Jacob Schön (10692813)
Angele Breithaupt (245016)
Dirk Höper (193333)
Jacqueline King (9340745)
Anne Pohlmann (505800)
Rokshana Parvin (8652624)
Klaus-Peter Behr (10692816)
Bernd-Andreas Schwarz (10692819)
Martin Beer (222377)
Jürgen Stech (245023)
Timm Harder (505801)
Christian Grund (371078)
Dokumenttyp: Image
Erscheinungsdatum: 2021
Schlagwörter: Biochemistry / Medicine / Microbiology / Science Policy / Infectious Diseases / Virology / Biological Sciences not elsewhere classified / 1N / trypsin-independent virus replication / Initial pathology investigations / HA / H 3 LPAIV / H 3N strain / N 1 neuraminidase-operated recruitment / pathogenicity / luciferase reporter assays show / H 3N virus / HPAIV / mouse brain-passaged laboratory strain / H 3N virus replicates / 6- aminohexanoic acid / Influenza viruses H 3N / Neuraminidase-associated plasminoge. / influenza viruses / tissue-restricted serine peptidases
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-26525417
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.1371/journal.ppat.1009490.g001