Genomic Regions Associated with IgE Levels against Culicoides spp. Antigens in Three Horse Breeds
Insect bite hypersensitivity (IBH), which is a cutaneous allergic reaction to antigens from Culicoides spp., is the most prevalent skin disorder in horses. Misdiagnosis is possible, as IBH is usually diagnosed based on clinical signs. Our study is the first to employ IgE levels against several recombinant Culicoides spp. allergens as an objective, independent, and quantitative phenotype to improve the power to detect genetic variants that underlie IBH. Genotypes of 200 Shetland ponies, 127 Icelandic horses, and 223 Belgian Warmblood horses were analyzed while using a mixed model approach. No s... Mehr ...
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Dokumenttyp: | Text |
Erscheinungsdatum: | 2019 |
Verlag/Hrsg.: |
Multidisciplinary Digital Publishing Institute
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Schlagwörter: | Belgian Warmblood horse / diagnostic ELISA test / genome-wide association study / Icelandic horse / IgE / insect bite hypersensitivity / Shetland pony / summer eczema |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26512674 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://doi.org/10.3390/genes10080597 |