Phylogenomic Investigation of Increasing Fluoroquinolone Resistance among Belgian Cases of Shigellosis between 2013 and 2018 Indicates Both Travel-Related Imports and Domestic Circulation
Shigellosis is an acute enteric infection caused mainly by the species Shigella flexneri and Shigella sonnei . Since surveillance of these pathogens indicated an increase in ciprofloxacin-resistant samples collected in Belgium between 2013 and 2018, a subset of 148 samples was analyzed with whole genome sequencing (WGS) to investigate their dispersion and underlying genomic features associated with ciprofloxacin resistance. A comparison between observed phenotypes and WGS-based resistance prediction to ciprofloxacin revealed perfect correspondence for all samples. Core genome multi-locus seque... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2021 |
Reihe/Periodikum: | Microorganisms, Vol 9, Iss 767, p 767 (2021) |
Verlag/Hrsg.: |
MDPI AG
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Schlagwörter: | Shigella / fluoroquinolones / ciprofloxacin / public health / national reference center / antimicrobial resistance / Biology (General) / QH301-705.5 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26501098 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://doi.org/10.3390/microorganisms9040767 |