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Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Wain, Louise V, Vaez, Ahmad, Jansen, Rick, Joehanes, Roby, van der Most, Peter J, Erzurumluoglu, A Mesut, O'Reilly, Paul F, Cabrera, Claudia P, Warren, Helen R, Rose, Lynda M, Verwoert, Germaine C, Hottenga, Jouke-Jan, Strawbridge, Rona J, Esko, Tonu, Arking, Dan E, Hwang, Shih-Jen, Guo, Xiuqing, Kutalik, Zoltan, Trompet, Stella, Shrine, Nick, Teumer, Alexander, Ried, Janina S, Bis, Joshua C, Smith, Albert V, Amin, Najaf, Nolte, Ilja M, Lyytikäinen, Leo-Pekka, Mahajan, Anubha, Wareham, Nicholas J, Hofer, Edith, Joshi, Peter K, Kristiansson, Kati, Traglia, Michela, Havulinna, Aki S, Goel, Anuj, Nalls, Mike A, Sõber, Siim, Vuckovic, Dragana, Luan, Jian'an, Del Greco M, Fabiola, Ayers, Kristin L, Marrugat, Jaume, Ruggiero, Daniela, Lopez, Lorna M, Niiranen, Teemu, Enroth, Stefan, Jackson, Anne U, Nelson, Christopher P, Huffman, Jennifer E, Zhang, Weihua, Marten, Jonathan, Gandin, Ilaria, Harris, Sarah E, Zemunik, Tatijana, Lu, Yingchang, Evangelou, Evangelos, Shah, Nabi, de Borst, Martin H, Mangino, Massimo, Prins, Bram P, Campbell, Archie, Li-Gao, Ruifang, Chauhan, Ganesh, Oldmeadow, Christopher, Abecasis, Gonçalo R, Abedi, Maryam, Barbieri, Caterina M, Barnes, Michael R, Batini, Chiara, Beilby, John, Blake, Tineka, Boehnke, Michael, Bottinger, Erwin P, Braund, Peter S, Brown, Morris, Brumat, Marco, Campbell, Harry, Chambers, John C, Cocca, Massimiliano, Collins, Francis S, Connell, John, Cordell, Heather J, Damman, Jeffrey J, Davies, Gail, de Geus, Eco J, de Mutsert, Renée, Deelen, Joris, Demirkale, Yusuf, Doney, Alex S F, Dörr, Marcus, Farrall, Martin, Ferreira, Teresa, Frånberg, Mattias, Gao, He, Giedraitis, Vilmantas, Gieger, Christian, Giulianini, Franco, Gow, Alan J, Hamsten, Anders, Harris, Tamara B, Hofman, Albert, Holliday, Elizabeth G, Hui, Jennie, Jarvelin, Marjo-Riitta, Johansson, Åsa, Johnson, Andrew D, Jousilahti, Pekka, Jula, Antti, Kähönen, Mika, Kathiresan, Sekar, Khaw, Kay-Tee, Kolcic, Ivana, Koskinen, Seppo, Langenberg, Claudia, Larson, Marty, Launer, Lenore J, Lehne, Benjamin, Liewald, David C M, Lin, Li, Lind, Lars, Mach, François, Mamasoula, Chrysovalanto, Menni, Cristina, Mifsud, Borbala, Milaneschi, Yuri, Morgan, Anna, Morris, Andrew D, Morrison, Alanna C, Munson, Peter J, Nandakumar, Priyanka, Nguyen, Quang Tri, Nutile, Teresa, Oldehinkel, Albertine J, Oostra, Ben A, Org, Elin, Padmanabhan, Sandosh, Palotie, Aarno, Paré, Guillaume, Pattie, Alison, Penninx, Brenda W J H, Poulter, Neil, Pramstaller, Peter P, Raitakari, Olli T, Ren, Meixia, Rice, Kenneth, Ridker, Paul M, Riese, Harriëtte, Ripatti, Samuli, Robino, Antonietta, Rotter, Jerome I, Rudan, Igor, Saba, Yasaman, Saint Pierre, Aude, Sala, Cinzia F, Sarin, Antti-Pekka, Schmidt, Reinhold E, Scott, Rodney J, Seelen, Marc A, Shields, Denis C, Siscovick, David, Sorice, Rossella, Stanton, Alice, Stott, David J, Sundström, Johan, Swertz, Morris a., Taylor, Kent D, Thom, Simon, Tzoulaki, Ioanna, Tzourio, Christophe, Uitterlinden, André G, Völker, Uwe, Vollenweider, Peter, Wild, Sarah, Willemsen, Gonneke, Wright, Alan F, Yao, Jie, Thériault, Sébastien, Conen, David, Attia, John R, Sever, Peter, Debette, Stéphanie, Mook-Kanamori, Dennis O, Zeggini, Eleftheria, Spector, Tim D, van der Harst, Pim, Palmer, Colin N A, Vergnaud, Anne-Claire, Loos, Ruth J F, Polasek, Ozren, Starr, John M, Girotto, Giorgia, Hayward, Caroline, Kooner, Jaspal S, Lindgren, Cecila M, Vitart, Veronique, Samani, Nilesh J, Tuomilehto, Jaakko, Gyllensten, Ulf, Knekt, Paul, Deary, Ian J, Ciullo, Marina, Elosua, Roberto, Keavney, Bernard D, Hicks, Andrew A, Scott, Robert A, Gasparini, Paolo, Laan, Maris, Liu, YongMei, Watkins, Hugh, Hartman, Catharina A, Salomaa, Veikko, Toniolo, Daniela, Perola, Markus, Wilson, James F, Schmidt, Helena, Zhao, Jing Hua, Lehtimäki, Terho, van Duijn, Cornelia M, Gudnason, Vilmundur, Psaty, Bruce M, Peters, Annette, Rettig, Rainer, James, Alan L, Jukema, J Wouter, Strachan, David P, Palmas, Walter, Metspalu, Andres, Ingelsson, Erik, Boomsma, Dorret I, Franco, Oscar H, Bochud, Murielle, Newton-Cheh, Christopher, Munroe, Patricia B, Elliott, Paul, Chasman, Daniel I, Chakravarti, Aravinda, Knight, Joanne, Morris, Andrew P, Levy, Daniel, Tobin, Martin D, Snieder, Harold, Caulfield, Mark J, Ehret, Georg B
Veröffentlicht in: Wain , L V , Vaez , A , Jansen , R , Joehanes , R , van der Most , P J , Erzurumluoglu , A M , O'Reilly , P F , Cabrera , C P , Warren , H R , Rose , L M , Verwoert , G C , Hottenga , J-J , Strawbridge , R J , Esko , T , Arking , D E , Hwang , S-J , Guo , X , Kutalik , Z , Trompet , S , Shrine , N , Teumer , A , Ried , J S , Bis , J C , Smith , A V , Amin , N , Nolte , I M , Lyytikäinen , L-P , Mahajan , A , Wareham , N J , Hofer , E , Joshi , P K , Kristiansson , K , Traglia , M , Havulinna , A S , Goel , A , Nalls , M A , Sõber , S , Vuckovic , D , Luan , J , Del Greco M , F , Ayers , K L , Marrugat , J , Ruggiero , D , Lopez , L M , Niiranen , T , Enroth , S , Jackson , A U , Nelson , C P , Huffman , J E , Zhang , W , Marten , J , Gandin , I , Harris , S E , Zemunik , T , Lu , Y , Evangelou , E , Shah , N , de Borst , M H , Mangino , M , Prins , B P , Campbell , A , Li-Gao , R , Chauhan , G , Oldmeadow , C , Abecasis , G R , Abedi , M , Barbieri , C M , Barnes , M R , Batini , C , Beilby , J , Blake , T , Boehnke , M , Bottinger , E P , Braund , P S , Brown , M , Brumat , M , Campbell , H , Chambers , J C , Cocca , M , Collins , F S , Connell , J , Cordell , H J , Damman , J J , Davies , G , de Geus , E J , de Mutsert , R , Deelen , J , Demirkale , Y , Doney , A S F , Dörr , M , Farrall , M , Ferreira , T , Frånberg , M , Gao , H , Giedraitis , V , Gieger , C , Giulianini , F , Gow , A J , Hamsten , A , Harris , T B , Hofman , A , Holliday , E G , Hui , J , Jarvelin , M-R , Johansson , Å , Johnson , A D , Jousilahti , P , Jula , A , Kähönen , M , Kathiresan , S , Khaw , K-T , Kolcic , I , Koskinen , S , Langenberg , C , Larson , M , Launer , L J , Lehne , B , Liewald , D C M , Lin , L , Lind , L , Mach , F , Mamasoula , C , Menni , C , Mifsud , B , Milaneschi , Y , Morgan , A , Morris , A D , Morrison , A C , Munson , P J , Nandakumar , P , Nguyen , Q T , Nutile , T , Oldehinkel , A J , Oostra , B A , Org , E , Padmanabhan , S , Palotie , A , Paré , G , Pattie , A , Penninx , B W J H , Poulter , N , Pramstaller , P P , Raitakari , O T , Ren , M , Rice , K , Ridker , P M , Riese , H , Ripatti , S , Robino , A , Rotter , J I , Rudan , I , Saba , Y , Saint Pierre , A , Sala , C F , Sarin , A-P , Schmidt , R E , Scott , R J , Seelen , M A , Shields , D C , Siscovick , D , Sorice , R , Stanton , A , Stott , D J , Sundström , J , Swertz , M A , Taylor , K D , Thom , S , Tzoulaki , I , Tzourio , C , Uitterlinden , A G , Völker , U , Vollenweider , P , Wild , S , Willemsen , G , Wright , A F , Yao , J , Thériault , S , Conen , D , Attia , J R , Sever , P , Debette , S , Mook-Kanamori , D O , Zeggini , E , Spector , T D , van der Harst , P , Palmer , C N A , Vergnaud , A-C , Loos , R J F , Polasek , O , Starr , J M , Girotto , G , Hayward , C , Kooner , J S , Lindgren , C M , Vitart , V , Samani , N J , Tuomilehto , J , Gyllensten , U , Knekt , P , Deary , I J , Ciullo , M , Elosua , R , Keavney , B D , Hicks , A A , Scott , R A , Gasparini , P , Laan , M , Liu , Y , Watkins , H , Hartman , C A , Salomaa , V , Toniolo , D , Perola , M , Wilson , J F , Schmidt , H , Zhao , J H , Lehtimäki , T , van Duijn , C M , Gudnason , V , Psaty , B M , Peters , A , Rettig , R , James , A L , Jukema , J W , Strachan , D P , Palmas , W , Metspalu , A , Ingelsson , E , Boomsma , D I , Franco , O H , Bochud , M , Newton-Cheh , C , Munroe , P B , Elliott , P , Chasman , D I , Chakravarti , A , Knight , J , Morris , A P , Levy , D , Tobin , M D , Snieder , H , Caulfield , M J & Ehret , G B 2017 , ' Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney ' , Hypertension , vol. 70 , no. 3 , pp. e4-e19 . https://doi.org/10.1161/HYPERTENSIONAHA.117.09438;
2017

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Genetic and Environmental Contributions to the Development of Childhood Aggression

Lubke, Gitta H, McArtor, Daniel B, Boomsma, Dorret I, Bartels, Meike
Veröffentlicht in: Lubke , G H , McArtor , D B , Boomsma , D I & Bartels , M 2018 , ' Genetic and Environmental Contributions to the Development of Childhood Aggression ' , Developmental Psychology , vol. 54 , no. 1 , pp. 39-50 . https://doi.org/10.1037/dev0000403;
2018

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Identification of context-dependent expression quantitative trait loci in whole blood

Zhernakova, Daria V, Deelen, Patrick, Vermaat, Martijn, van Iterson, Maarten, van Galen, Michiel, Arindrarto, Wibowo, van 't Hof, Peter, Mei, Hailiang, van Dijk, Freerk, Westra, Harm-Jan, Bonder, Marc Jan, van Rooij, Jeroen, Verkerk, Marijn, Jhamai, P Mila, Moed, Matthijs, Kielbasa, Szymon M, Bot, Jan, Nooren, Irene, Pool, René, van Dongen, J., Hottenga, Jouke J, Stehouwer, Coen D A, van der Kallen, Carla J H, Schalkwijk, Casper G, Zhernakova, Alexandra, Li, Yang, Tigchelaar, Ettje F, de Klein, Niek, Beekman, Marian, Deelen, Joris, van Heemst, Diana, van den Berg, Leonard H, Hofman, Albert, Uitterlinden, André G, Van Greevenbroek, Marleen J., Veldink, Jan H, Boomsma, Dorret I, van Duijn, Cornelia M, Wijmenga, Cisca, Slagboom, P. Eline, Swertz, Morris a., Isaacs, Aaron, van Meurs, Joyce B J, Jansen, Rick, Heijmans, Bastiaan T, ’t Hoen, Peter a.C, Franke, Lude
Veröffentlicht in: Zhernakova , D V , Deelen , P , Vermaat , M , van Iterson , M , van Galen , M , Arindrarto , W , van 't Hof , P , Mei , H , van Dijk , F , Westra , H-J , Bonder , M J , van Rooij , J , Verkerk , M , Jhamai , P M , Moed , M , Kielbasa , S M , Bot , J , Nooren , I , Pool , R , van Dongen , J , Hottenga , J J , Stehouwer , C D A , van der Kallen , C J H , Schalkwijk , C G , Zhernakova , A , Li , Y , Tigchelaar , E F , de Klein , N , Beekman , M , Deelen , J , van Heemst , D , van den Berg , L H , Hofman , A , Uitterlinden , A G , Van Greevenbroek , M J , Veldink , J H , Boomsma , D I , van Duijn , C M , Wijmenga , C , Slagboom , P E , Swertz , M A , Isaacs , A , van Meurs , J B J , Jansen , R , Heijmans , B T , ’t Hoen , P A C & Franke , L 2017 , ' Identification of context-dependent expression quantitative trait loci in whole blood ' , Nature Genetics , vol. 49 , no. 1 , pp. 139-145 . https://doi.org/10.1038/ng.3737;
2017

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Differential gene expression patterns between smokers and non-smokers:cause or consequence?

Vink, Jacqueline M, Jansen, Rick, Brooks, Andy, Willemsen, Gonneke, van Grootheest, Gerard, de Geus, Eco, Smit, Jan H, Penninx, Brenda W, Boomsma, Dorret I
Veröffentlicht in: Vink , J M , Jansen , R , Brooks , A , Willemsen , G , van Grootheest , G , de Geus , E , Smit , J H , Penninx , B W & Boomsma , D I 2017 , ' Differential gene expression patterns between smokers and non-smokers : cause or consequence? ' , Addiction Biology , vol. 22 , no. 2 , pp. 550-560 . https://doi.org/10.1111/adb.12322;
2017

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Using Clinical Characteristics to Identify Which Patients With Major Depressive Disorder Have a Higher Genetic Load for Three Psychiatric Disorders

Verduijn, Judith, Milaneschi, Yuri, Peyrot, Wouter J, Hottenga, Jouke Jan, Abdellaoui, A., de Geus, Eco J C, Smit, Johannes H, Breen, Gerome, Lewis, Cathryn M, Boomsma, Dorret I, Beekman, Aartjan T F, Penninx, Brenda W J H
Veröffentlicht in: Verduijn , J , Milaneschi , Y , Peyrot , W J , Hottenga , J J , Abdellaoui , A , de Geus , E J C , Smit , J H , Breen , G , Lewis , C M , Boomsma , D I , Beekman , A T F & Penninx , B W J H 2017 , ' Using Clinical Characteristics to Identify Which Patients With Major Depressive Disorder Have a Higher Genetic Load for Three Psychiatric Disorders ' , Biological Psychiatry , vol. 81 , no. 4 , pp. 316-324 . https://doi.org/10.1016/j.biopsych.2016.05.024;
2017

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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, Peter K, Pirastu, Nicola, Kentistou, Katherine A, Fischer, Krista, Hofer, Edith, Schraut, Katharina E, Clark, David W, Nutile, Teresa, Barnes, Catriona L K, Timmers, Paul R H J, Shen, Xia, Gandin, Ilaria, McDaid, Aaron F, Hansen, Thomas Folkmann, Gordon, Scott D, Giulianini, Franco, Boutin, Thibaud S, Abdellaoui, Abdel, Zhao, Wei, Medina-Gomez, Carolina, Bartz, Traci M, Trompet, Stella, Lange, Leslie A, Raffield, Laura, van der Spek, Ashley, Galesloot, Tessel E, Proitsi, Petroula, Yanek, Lisa R, Bielak, Lawrence F, Payton, Antony, Murgia, Federico, Concas, Maria Pina, Biino, Ginevra, Tajuddin, Salman M, Seppälä, Ilkka, Amin, Najaf, Boerwinkle, Eric, Børglum, Anders D, Campbell, Archie, Demerath, Ellen W, Demuth, Ilja, Faul, Jessica D, Ford, Ian, Gialluisi, Alessandro, Gögele, Martin, Graff, MariaElisa, Hingorani, Aroon, Hottenga, Jouke-Jan, Hougaard, David M, Hurme, Mikko A, Ikram, M Arfan, Jylhä, Marja, Kuh, Diana, Ligthart, Lannie, Lill, Christina M, Lindenberger, Ulman, Lumley, Thomas, Mägi, Reedik, Marques-Vidal, Pedro, Medland, Sarah E, Milani, Lili, Nagy, Reka, Ollier, William E R, Peyser, Patricia A, Pramstaller, Peter P, Ridker, Paul M, Rivadeneira, Fernando, Ruggiero, Daniela, Saba, Yasaman, Schmidt, Reinhold, Schmidt, Helena, Slagboom, P Eline, Smith, Blair H, Smith, Jennifer A, Sotoodehnia, Nona, Steinhagen-Thiessen, Elisabeth, van Rooij, Frank J A, Verbeek, André L, Vermeulen, Sita H, Vollenweider, Peter, Wang, Yunpeng, Werge, Thomas, Whitfield, John B, Zonderman, Alan B, Lehtimäki, Terho, Evans, Michele K, Pirastu, Mario, Fuchsberger, Christian, Bertram, Lars, Pendleton, Neil, Kardia, Sharon L R, Ciullo, Marina, Becker, Diane M, Wong, Andrew, Psaty, Bruce M, van Duijn, Cornelia M, Wilson, James G, Jukema, J Wouter, Kiemeney, Lambertus, Uitterlinden, André G, Franceschini, Nora, North, Kari E, Weir, David R, Metspalu, Andres, Boomsma, Dorret I, Hayward, Caroline, Chasman, Daniel, Martin, Nicholas G, Sattar, Naveed, Campbell, Harry, Esko, Tōnu, Kutalik, Zoltán, Wilson, James F
Veröffentlicht in: Joshi , P K , Pirastu , N , Kentistou , K A , Fischer , K , Hofer , E , Schraut , K E , Clark , D W , Nutile , T , Barnes , C L K , Timmers , P R H J , Shen , X , Gandin , I , McDaid , A F , Hansen , T F , Gordon , S D , Giulianini , F , Boutin , T S , Abdellaoui , A , Zhao , W , Medina-Gomez , C , Bartz , T M , Trompet , S , Lange , L A , Raffield , L , van der Spek , A , Galesloot , T E , Proitsi , P , Yanek , L R , Bielak , L F , Payton , A , Murgia , F , Concas , M P , Biino , G , Tajuddin , S M , Seppälä , I , Amin , N , Boerwinkle , E , Børglum , A D , Campbell , A , Demerath , E W , Demuth , I , Faul , J D , Ford , I , Gialluisi , A , Gögele , M , Graff , M , Hingorani , A , Hottenga , J-J , Hougaard , D M , Hurme , M A , Ikram , M A , Jylhä , M , Kuh , D , Ligthart , L , Lill , C M , Lindenberger , U , Lumley , T , Mägi , R , Marques-Vidal , P , Medland , S E , Milani , L , Nagy , R , Ollier , W E R , Peyser , P A , Pramstaller , P P , Ridker , P M , Rivadeneira , F , Ruggiero , D , Saba , Y , Schmidt , R , Schmidt , H , Slagboom , P E , Smith , B H , Smith , J A , Sotoodehnia , N , Steinhagen-Thiessen , E , van Rooij , F J A , Verbeek , A L , Vermeulen , S H , Vollenweider , P , Wang , Y , Werge , T , Whitfield , J B , Zonderman , A B , Lehtimäki , T , Evans , M K , Pirastu , M , Fuchsberger , C , Bertram , L , Pendleton , N , Kardia , S L R , Ciullo , M , Becker , D M , Wong , A , Psaty , B M , van Duijn , C M , Wilson , J G , Jukema , J W , Kiemeney , L , Uitterlinden , A G , Franceschini , N , North , K E , Weir , D R , Metspalu , A , Boomsma , D I , Hayward , C , Chasman , D , Martin , N G , Sattar , N , Campbell , H , Esko , T , Kutalik , Z & Wilson , J F 2017 , ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ' , Nature Communications , vol. 8 , no. 1 , 910 , pp. 910 . https://doi.org/10.1038/s41467-017-00934-5;
2017

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DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

Richard, Melissa A, Huan, Tianxiao, Ligthart, Symen, Gondalia, Rahul, Jhun, Min A, Brody, Jennifer A, Irvin, Marguerite R, Marioni, Riccardo, Shen, Jincheng, Tsai, Pei-Chien, Montasser, May E, Jia, Yucheng, Syme, Catriona, Salfati, Elias L, Boerwinkle, Eric, Guan, Weihua, Mosley, Thomas H, Bressler, Jan, Morrison, Alanna C, Liu, Chunyu, Mendelson, Michael M, Uitterlinden, André G, van Meurs, Joyce B, Franco, Oscar H, Zhang, Guosheng, Li, Yun, Stewart, James D, Bis, Joshua C, Psaty, Bruce M, Chen, Yii-Der Ida, Kardia, Sharon L R, Zhao, Wei, Turner, Stephen T, Absher, Devin, Aslibekyan, Stella, Starr, John M, McRae, Allan F, Hou, Lifang, Just, Allan C, Schwartz, Joel D, Vokonas, Pantel S, Menni, Cristina, Spector, Tim D, Shuldiner, Alan, Damcott, Coleen M, Rotter, Jerome I, Boomsma, D.I., Pool, R., van Dongen, J., Hottenga, J.J.
Veröffentlicht in: Richard , M A , Huan , T , Ligthart , S , Gondalia , R , Jhun , M A , Brody , J A , Irvin , M R , Marioni , R , Shen , J , Tsai , P-C , Montasser , M E , Jia , Y , Syme , C , Salfati , E L , Boerwinkle , E , Guan , W , Mosley , T H , Bressler , J , Morrison , A C , Liu , C , Mendelson , M M , Uitterlinden , A G , van Meurs , J B , Franco , O H , Zhang , G , Li , Y , Stewart , J D , Bis , J C , Psaty , B M , Chen , Y-D I , Kardia , S L R , Zhao , W , Turner , S T , Absher , D , Aslibekyan , S , Starr , J M , McRae , A F , Hou , L , Just , A C , Schwartz , J D , Vokonas , P S , Menni , C , Spector , T D , Shuldiner , A , Damcott , C M , Rotter , J I , BIOS Consortium , Boomsma , D I , Pool , R , van Dongen , J & Hottenga , J J 2017 , ' DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation ' , American Journal of Human Genetics , vol. 101 , no. 6 , pp. 888-902 . https://doi.org/10.1016/j.ajhg.2017.09.028;
2017

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Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations:A transethnic genome-wide meta-analysis

Wheeler, Eleanor, Leong, Aaron, Liu, Ching-Ti, Hivert, Marie-France, Strawbridge, Rona J, Podmore, Clara, Li, Man, Yao, Jie, Sim, Xueling, Hong, Jaeyoung, Chu, Audrey Y, Zhang, Weihua, Wang, Xu, Chen, Peng, Maruthur, Nisa M, Porneala, Bianca C, Sharp, Stephen J, Jia, Yucheng, Kabagambe, Edmond K, Chang, Li-Ching, Chen, Wei-Min, Elks, Cathy E, Evans, Daniel S, Fan, Qiao, Giulianini, Franco, Go, Min Jin, Hottenga, Jouke-Jan, Hu, Yao, Jackson, Anne U, Kanoni, Stavroula, Kim, Young Jin, Kleber, Marcus E, Ladenvall, Claes, Lecoeur, Cecile, Lim, Sing-Hui, Lu, Yingchang, Mahajan, Anubha, Marzi, Carola, Nalls, Mike A, Navarro, Pau, Nolte, Ilja M, Rose, Lynda M, Rybin, Denis V, Sanna, Serena, Shi, Yuan, Stram, Daniel O, Willemsen, Gonneke, Boomsma, Dorret I, de Geus, Eco J C, van Dam, Rob M
Veröffentlicht in: Wheeler , E , Leong , A , Liu , C-T , Hivert , M-F , Strawbridge , R J , Podmore , C , Li , M , Yao , J , Sim , X , Hong , J , Chu , A Y , Zhang , W , Wang , X , Chen , P , Maruthur , N M , Porneala , B C , Sharp , S J , Jia , Y , Kabagambe , E K , Chang , L-C , Chen , W-M , Elks , C E , Evans , D S , Fan , Q , Giulianini , F , Go , M J , Hottenga , J-J , Hu , Y , Jackson , A U , Kanoni , S , Kim , Y J , Kleber , M E , Ladenvall , C , Lecoeur , C , Lim , S-H , Lu , Y , Mahajan , A , Marzi , C , Nalls , M A , Navarro , P , Nolte , I M , Rose , L M , Rybin , D V , Sanna , S , Shi , Y , Stram , D O , Willemsen , G , Boomsma , D I , de Geus , E J C , van Dam , R M & EPIC-CVD Consortium 2017 , ' Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations : A transethnic genome-wide meta-analysis ' , PLoS Medicine , vol. 14 , no. 9 , e1002383 , pp. e1002383 . https://doi.org/10.1371/journal.pmed.1002383;
2017

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Metabolite ratios as potential biomarkers for type 2 diabetes:a DIRECT study

Molnos, Sophie, Wahl, Simone, Haid, Mark, Eekhoff, E Marelise W, Pool, René, Floegel, Anna, Deelen, Joris, Much, Daniela, Prehn, Cornelia, Breier, Michaela, Draisma, Harmen H, van Leeuwen, Nienke, Simonis-Bik, Annemarie M C, Jonsson, Anna, Willemsen, Gonneke, Bernigau, Wolfgang, Wang-Sattler, Rui, Suhre, Karsten, Peters, Annette, Thorand, Barbara, Herder, Christian, Rathmann, Wolfgang, Roden, Michael, Gieger, Christian, Kramer, Mark H H, van Heemst, Diana, Pedersen, Helle K, Gudmundsdottir, Valborg, Schulze, Matthias B, Pischon, Tobias, de Geus, Eco J C, Boeing, Heiner, Boomsma, Dorret I, Ziegler, Anette G, Slagboom, P. Eline, Hummel, Sandra, Beekman, Marian, Grallert, Harald, Brunak, Søren, McCarthy, Mark I, Gupta, Ramneek, Pearson, Ewan R, Adamski, Jerzy, 't Hart, Leen M
Veröffentlicht in: Molnos , S , Wahl , S , Haid , M , Eekhoff , E M W , Pool , R , Floegel , A , Deelen , J , Much , D , Prehn , C , Breier , M , Draisma , H H , van Leeuwen , N , Simonis-Bik , A M C , Jonsson , A , Willemsen , G , Bernigau , W , Wang-Sattler , R , Suhre , K , Peters , A , Thorand , B , Herder , C , Rathmann , W , Roden , M , Gieger , C , Kramer , M H H , van Heemst , D , Pedersen , H K , Gudmundsdottir , V , Schulze , M B , Pischon , T , de Geus , E J C , Boeing , H , Boomsma , D I , Ziegler , A G , Slagboom , P E , Hummel , S , Beekman , M , Grallert , H , Brunak , S , McCarthy , M I , Gupta , R , Pearson , E R , Adamski , J & 't Hart , L M 2018 , ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ' , Diabetologia , vol. 61 , no. 1 , pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7;
2018

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Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion:A DIRECT study

Gudmundsdottir, Valborg, Pedersen, Helle Krogh, Allebrandt, Karla Viviani, Brorsson, Caroline, van Leeuwen, Nienke, Banasik, Karina, Mahajan, Anubha, Groves, Christopher J, van de Bunt, Martijn, Dawed, Adem Y, Fritsche, Andreas, Staiger, Harald, Simonis-Bik, Annemarie M C, Deelen, Joris, Kramer, Mark H H, Dietrich, Axel, Hübschle, Thomas, Willemsen, Gonneke, Häring, Hans-Ulrich, de Geus, Eco J C, Boomsma, Dorret I, Eekhoff, Elisabeth M W, Ferrer, Jorge, McCarthy, Mark I, Pearson, Ewan R, Gupta, Ramneek, Brunak, Søren, 't Hart, Leen M
Veröffentlicht in: Gudmundsdottir , V , Pedersen , H K , Allebrandt , K V , Brorsson , C , van Leeuwen , N , Banasik , K , Mahajan , A , Groves , C J , van de Bunt , M , Dawed , A Y , Fritsche , A , Staiger , H , Simonis-Bik , A M C , Deelen , J , Kramer , M H H , Dietrich , A , Hübschle , T , Willemsen , G , Häring , H-U , de Geus , E J C , Boomsma , D I , Eekhoff , E M W , Ferrer , J , McCarthy , M I , Pearson , E R , Gupta , R , Brunak , S & 't Hart , L M 2018 , ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ' , PLoS ONE , vol. 13 , no. 1 , e0189886 , pp. e0189886 . https://doi.org/10.1371/journal.pone.0189886;
2018