1.
The specific implementation of the BioRS function in the molecular biological aspect.
Molecular biological illustration of the idea of evolutionary search with BioRS.
General idea of alternative structures of aptamers binding the same ligand and its specific implementation scheme for the BioRS function.
Extended (competitive) version of BioRS, implementing alternative aptamer structures and interference.
Idea of the search for a domain/motif within the range from 1 to W positions (in the window) instead of an only predetermined position.
Effectiveness of evolutionary GA search (mutations only) with ( μ , λ ) selection, μ / λ = 0.4, 4 domains, 6+4 defined positions out of 26, W = 220 at varying mutation rate and pop...
RMHC: Effectiveness vs mutation rate.
In silico tests with parallel RMHC: Effectiveness vs number of parallel processes.
Block diagram of the experimental setup.
Schemes of the RR (left) and RS (right) functions.