Originalkatalog | Verfügbarkeit prüfen

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, van Dongen, J.
Veröffentlicht in: Qi , T , Wu , Y , Zeng , J , Zhang , F , Xue , A , Jiang , L , Zhu , Z , Kemper , K , Yengo , L , Zheng , Z , van Dongen , J & eQTLGen Consortium 2018 , ' Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood ' , Nature Communications , vol. 9 , no. 1 , 2282 . https://doi.org/10.1038/s41467-018-04558-1;
2018

Originalkatalog | Verfügbarkeit prüfen

Association Between Population Density and Genetic Risk for Schizophrenia

Colodro-Conde, Lucía, Couvy-Duchesne, Baptiste, Whitfield, John B., Streit, Fabian, Gordon, Scott, Kemper, Kathryn E., Yengo, Loic, Zheng, Zhili, Trzaskowski, Maciej, De Zeeuw, Eveline L., Nivard, Michel G., Das, Marjolijn, Neale, Rachel E., MacGregor, Stuart, Olsen, Catherine M., Whiteman, David C., Boomsma, Dorret I., Yang, Jian, Rietschel, Marcella, McGrath, John J., Medland, Sarah E., Martin, Nicholas G.
Veröffentlicht in: Colodro-Conde , L , Couvy-Duchesne , B , Whitfield , J B , Streit , F , Gordon , S , Kemper , K E , Yengo , L , Zheng , Z , Trzaskowski , M , De Zeeuw , E L , Nivard , M G , Das , M , Neale , R E , MacGregor , S , Olsen , C M , Whiteman , D C , Boomsma , D I , Yang , J , Rietschel , M , McGrath , J J , Medland , S E & Martin , N G 2018 , ' Association Between Population Density and Genetic Risk for Schizophrenia ' , JAMA Psychiatry , vol. 75 , no. 9 , pp. 901-910 . https://doi.org/10.1001/jamapsychiatry.2018.1581;
2018

Originalkatalog | Verfügbarkeit prüfen

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

Ferreira, Manuel A, Vonk, Judith M, Baurecht, Hansjörg, Marenholz, Ingo, Tian, Chao, Hoffman, Joshua D, Helmer, Quinta, Tillander, Annika, Ullemar, Vilhelmina, van Dongen, Jenny, Lu, Yi, Rüschendorf, Franz, Esparza-Gordillo, Jorge, Medway, Chris W, Mountjoy, Edward, Burrows, Kimberley, Hummel, Oliver, Grosche, Sarah, Brumpton, Ben M, Witte, John S, Hottenga, Jouke-Jan, Willemsen, Gonneke, Zheng, Jie, Rodríguez, Elke, Hotze, Melanie, Franke, Andre, Revez, Joana A, Beesley, Jonathan, Matheson, Melanie C, Dharmage, Shyamali C, Bain, Lisa M, Fritsche, Lars G, Gabrielsen, Maiken E, Balliu, Brunilda, Nielsen, Jonas B, Zhou, Wei, Hveem, Kristian, Langhammer, Arnulf, Holmen, Oddgeir L, Løset, Mari, Abecasis, Gonçalo R, Willer, Cristen J, Arnold, Andreas, Homuth, Georg, Schmidt, Carsten O, Thompson, Philip J, Martin, Nicholas G, Duffy, David L, Novak, Natalija, Boomsma, Dorret I
Veröffentlicht in: Ferreira , M A , Vonk , J M , Baurecht , H , Marenholz , I , Tian , C , Hoffman , J D , Helmer , Q , Tillander , A , Ullemar , V , van Dongen , J , Lu , Y , Rüschendorf , F , Esparza-Gordillo , J , Medway , C W , Mountjoy , E , Burrows , K , Hummel , O , Grosche , S , Brumpton , B M , Witte , J S , Hottenga , J-J , Willemsen , G , Zheng , J , Rodríguez , E , Hotze , M , Franke , A , Revez , J A , Beesley , J , Matheson , M C , Dharmage , S C , Bain , L M , Fritsche , L G , Gabrielsen , M E , Balliu , B , Nielsen , J B , Zhou , W , Hveem , K , Langhammer , A , Holmen , O L , Løset , M , Abecasis , G R , Willer , C J , Arnold , A , Homuth , G , Schmidt , C O , Thompson , P J , Martin , N G , Duffy , D L , Novak , N , Boomsma , D I & 23andMe Research Team 2017 , ' Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology ' , Nature Genetics , vol. 49 , no. 12 , pp. 1752-1757 . https://doi.org/10.1038/ng.3985;
2017

Originalkatalog | Verfügbarkeit prüfen

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D.P., Curtin, J.A., Bonnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A.C., Thyssen, J.P., den Dekker, H.T., Ferreira, M.A., Altmaier, E., Sleiman, P.M.A., Xiao, F.L., Gonzalez, J.R., Marenholz, I., Kalb, B., Pino-Yanes, M., Xu, C., Carstensen, L., Groen-Blokhuis, M.M., Venturini, C., Pennell, C.E., Barton, S.J., Levin, A.M., Curjuric, I., Bustamante, M., Kreiner-Moller, E., Lockett, G.A., Bacelis, J., Bunyavanich, S., Myers, R.A., Matanovic, A., Kumar, A., Tung, J.Y., Hirota, T., Kubo, M., McArdle, W.L., Henderson, A.J., Kemp, J.P., Zheng, J., Smith, G.D., Rueschendorf, F., Bauerfeind, A., Lee-Kirsch, M.A., Arnold, A., Homuth, G., Schmidt, C.O., Mangold, E., Cichon, S., Keil, T., Rodriguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Foelster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L.L., Grarup, N., de Jongste, J.C., Rivadeneira, F., Hofman, A., Jaddoe, V.W.V., Pasmans, S.G.M.A., Elbert, N.J., Uitterlinden, A. G., Marks, G.B., Thompson, P.J., Matheson, M.C., Robertson, C.F., Ried, J.S., Li, J., Zuo, X.B., Zheng, X.D., Yin, X.Y., Sun, L.D., McAleer, M.A., O'Regan, G.M., Fahy, C.M.R., Campbell, L.E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D.S., Feenstra, B., Geller, F., Hottenga, J.J., Middeldorp, C.M., Hysi, P., Bataille, V., Spector, T., Tiesler, C.M.T., Thiering, E., Pahukasahasram, B., Yang, J.J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C.L., Myhre, R., Nystad, W., Custovic, A., Weiss, S.T., Meyers, D.A., Soederhaell, C., Melen, E., Ober, C., Raby, B.A., Simpson, A., Jacobsson, B., Holloway, J.W., Bisgaard, H., Sunyer, J., Probst-Hensch, N.M., Williams, L.K., Godfrey, K.M., Wang, C.A., Boomsma, D.I., Melbye, M., Koppelman, G.H., Jarvis, D., McLean, W.H.I., Irvine, A.D., Zhang, X.J., Hakonarson, H., Gieger, C., Burchard, E.G., Martin, N.G., Duijts, L., Linneberg, A., Jarvelin, M., Noethen, M.M., Lau, S., Huebner, N., Lee, Y., Tamari, M., Hinds, D.A., Glass, D., Brown, S.J., Heinrich, J., Evans, D.M., Weidinger, S.
Veröffentlicht in: Paternoster , L , Standl , M , Waage , J , Baurecht , H , Hotze , M , Strachan , D P , Curtin , J A , Bonnelykke , K , Tian , C , Takahashi , A , Esparza-Gordillo , J , Alves , A C , Thyssen , J P , den Dekker , H T , Ferreira , M A , Altmaier , E , Sleiman , P M A , Xiao , F L , Gonzalez , J R , Marenholz , I , Kalb , B , Pino-Yanes , M , Xu , C , Carstensen , L , Groen-Blokhuis , M M , Venturini , C , Pennell , C E , Barton , S J , Levin , A M , Curjuric , I , Bustamante , M , Kreiner-Moller , E , Lockett , G A , Bacelis , J , Bunyavanich , S , Myers , R A , Matanovic , A , Kumar , A , Tung , J Y , Hirota , T , Kubo , M , McArdle , W L , Henderson , A J , Kemp , J P , Zheng , J , Smith , G D , Rueschendorf , F , Bauerfeind , A , Lee-Kirsch , M A , Arnold , A , Homuth , G , Schmidt , C O , Mangold , E , Cichon , S , Keil , T , Rodriguez , E , Peters , A , Franke , A , Lieb , W , Novak , N , Foelster-Holst , R , Horikoshi , M , Pekkanen , J , Sebert , S , Husemoen , L L , Grarup , N , de Jongste , J C , Rivadeneira , F , Hofman , A , Jaddoe , V W V , Pasmans , S G M A , Elbert , N J , Uitterlinden , A G , Marks , G B , Thompson , P J , Matheson , M C , Robertson , C F , Ried , J S , Li , J , Zuo , X B , Zheng , X D , Yin , X Y , Sun , L D , McAleer , M A , O'Regan , G M , Fahy , C M R , Campbell , L E , Macek , M , Kurek , M , Hu , D , Eng , C , Postma , D S , Feenstra , B , Geller , F , Hottenga , J J , Middeldorp , C M , Hysi , P , Bataille , V , Spector , T , Tiesler , C M T , Thiering , E , Pahukasahasram , B , Yang , J J , Imboden , M , Huntsman , S , Vilor-Tejedor , N , Relton , C L , Myhre , R , Nystad , W , Custovic , A , Weiss , S T , Meyers , D A , Soederhaell , C , Melen , E , Ober , C , Raby , B A , Simpson , A , Jacobsson , B , Holloway , J W , Bisgaard , H , Sunyer , J , Probst-Hensch , N M , Williams , L K , Godfrey , K M , Wang , C A , Boomsma , D I , Melbye , M , Koppelman , G H , Jarvis , D , McLean , W H I , Irvine , A D , Zhang , X J , Hakonarson , H , Gieger , C , Burchard , E G , Martin , N G , Duijts , L , Linneberg , A , Jarvelin , M , Noethen , M M , Lau , S , Huebner , N , Lee , Y , Tamari , M , Hinds , D A , Glass , D , Brown , S J , Heinrich , J , Evans , D M & Weidinger , S 2015 , ' Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis ' , Nature Genetics , vol. 47 , no. 12 , pp. 1449-1456 . https://doi.org/10.1038/ng.3424;
2015

Originalkatalog | Verfügbarkeit prüfen

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

Day, F.R., Ruth, K.S., Thompson, D.J., Lunetta, K.L., Pervjakova, N., Chasman, D.I., Stolk, L., Finucane, H.K., Sulem, P., Bulik-Sullivan, B.K., Esko, T., Johnson, A.D., Elks, C.E., Franceschini, N., He, C., Altmaier, E., Brody, J.A., Franke, L.L., Huffman, J.E., Keller, M.F., McArdle, P.F., Nutile, T., Porcu, E., Robino, A., Rose, L.M., Schick, U.M., Smith, J.A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J.J., Mangino, M., Smith, A.V., Tanaka, T., Abecasis, G.R., Andrulis, I.L., Anton-Culver, H., Antoniou, A.C., Arndt, V., Arnold, A.M., Barbieri, C., Beckmann, M.W., Beeghly-Fadiel, A., Benitez, J., Bernstein, L., Bielinski, S.J., Blomqvist, C., Boerwinkle, E., Bogdanova, N.V., Bojesen, S.E., Bolla, M.K., Borresen-Dale, A.L., Boutin, T.S., Brauch, H., Brenner, H., Brüning, T., Burwinkel, B., Campbell, A., Campbell, H., Chanock, S.J., Chapman, J.R., Ida Chen, Y.D., Chenevix-Trench, G., Couch, F.J., Coviello, A.D., Cox, A., Czene, K., Darabi, H., De Vivo, I., Demerath, E.W., Dennis, J., Devilee, P., Dörk, T., dos-Santos-Silva, I., Dunning, A.M., Eicher, J.D., Fasching, P.A., Faul, J.D., Figueroa, J., Flesch-Janys, D., Gandin, I., Garcia, M.E., García-Closas, M., Giles, G.G., Girotto, G.G., Goldberg, M.S., González-Neira, A., Goodarzi, M.O., Grove, M.L., Gudbjartsson, D.F., Guénel, P., Guo, X., Haiman, C.A., Hall, P., Hamann, U., Henderson, B.E., Hocking, L.J., Hofman, A., Homuth, G., Hooning, M.J., Hopper, J.L., Hu, F.B., Huang, J., Humphreys, K., Hunter, D.J., Jakubowska, A., Jones, S.E., Kabisch, M., Karasik, D., Knight, J.A., Kolcic, I., Kooperberg, C., Kosma, V.M., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J., Li, X., Lindström, S., Liu, Y., Luan, J., Lubinski, J., Mägi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J., Martin, N.G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L., Müller-Nurasyid, M., Nalls, M., Neale, B.M., Nevanlinna, H., Neven, P., Newman, A.B., Nordestgaard, B.G., Olson, J.E., Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P.D.P., Pirastu, N.N., Pirie, A., Pistis, G., Polasek, O., Porteous, D., Psaty, B.M., Pylkäs, K., Radice, P., Raffel, L.J., Rivadeneira, F., Rudan, I., Rudolph, A., Ruggiero, D., Sala, C.F., Sanna, S., Sawyer, E.J., Schlessinger, D., Schmidt, M.K., Schmidt, F., Schmutzler, R.K., Schoemaker, M.J., Scott, R.A., Seynaeve, C.M., Simard, J., Sorice, R., Southey, M.C., Stöckl, D., Strauch, K., Swerdlow, A., Taylor, K.D., Thorsteinsdottir, U., Toland, A.E., Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S.T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G., Wilson, J.F., Winqvist, R., Wolffenbuttel, B.H.R., Wright, A.F., Yannoukakos, D., Zemunik, T., Zheng, W., Zygmunt, M., Bergmann, S., Boomsma, D.I., Buring, J.E., Ferrucci, L., Montgomery, G.W., Gudnason, V., Spector, T.D., van Duijn, C.M., Alizadeh, BZ, Ciullo, M., Crisponi, L., Easton, D.F., Gasparini, P.P., Gieger, C., Harris, T.B., Hayward, C., Kardia, S.L.R., Kraft, P., McKnight, B., Metspalu, A., Morrison, A.C., Reiner, A.P., Ridker, P.M., Rotter, J.I., Toniolo, D., Uitterlinden, A.G., Ulivi, S., Völzke, H., Wareham, N.J., Weir, D.R., Yerges-Armstrong, L.M., Price, A.L., Stefansson, K., Visser, J.A., Ong, K.K., Chang-Claude, J., Murabito, J.M.M., Perry, J.R.B., Murray, A.
Veröffentlicht in: Day , F R , Ruth , K S , Thompson , D J , Lunetta , K L , Pervjakova , N , Chasman , D I , Stolk , L , Finucane , H K , Sulem , P , Bulik-Sullivan , B K , Esko , T , Johnson , A D , Elks , C E , Franceschini , N , He , C , Altmaier , E , Brody , J A , Franke , L L , Huffman , J E , Keller , M F , McArdle , P F , Nutile , T , Porcu , E , Robino , A , Rose , L M , Schick , U M , Smith , J A , Teumer , A , Traglia , M , Vuckovic , D , Yao , J , Zhao , W , Albrecht , E , Amin , N , Corre , T , Hottenga , J J , Mangino , M , Smith , A V , Tanaka , T , Abecasis , G R , Andrulis , I L , Anton-Culver , H , Antoniou , A C , Arndt , V , Arnold , A M , Barbieri , C , Beckmann , M W , Beeghly-Fadiel , A , Benitez , J , Bernstein , L , Bielinski , S J , Blomqvist , C , Boerwinkle , E , Bogdanova , N V , Bojesen , S E , Bolla , M K , Borresen-Dale , A L , Boutin , T S , Brauch , H , Brenner , H , Brüning , T , Burwinkel , B , Campbell , A , Campbell , H , Chanock , S J , Chapman , J R , Ida Chen , Y D , Chenevix-Trench , G , Couch , F J , Coviello , A D , Cox , A , Czene , K , Darabi , H , De Vivo , I , Demerath , E W , Dennis , J , Devilee , P , Dörk , T , dos-Santos-Silva , I , Dunning , A M , Eicher , J D , Fasching , P A , Faul , J D , Figueroa , J , Flesch-Janys , D , Gandin , I , Garcia , M E , García-Closas , M , Giles , G G , Girotto , G G , Goldberg , M S , González-Neira , A , Goodarzi , M O , Grove , M L , Gudbjartsson , D F , Guénel , P , Guo , X , Haiman , C A , Hall , P , Hamann , U , Henderson , B E , Hocking , L J , Hofman , A , Homuth , G , Hooning , M J , Hopper , J L , Hu , F B , Huang , J , Humphreys , K , Hunter , D J , Jakubowska , A , Jones , S E , Kabisch , M , Karasik , D , Knight , J A , Kolcic , I , Kooperberg , C , Kosma , V M , Kriebel , J , Kristensen , V , Lambrechts , D , Langenberg , C , Li , J , Li , X , Lindström , S , Liu , Y , Luan , J , Lubinski , J , Mägi , R , Mannermaa , A , Manz , J , Margolin , S , Marten , J , Martin , N G , Masciullo , C , Meindl , A , Michailidou , K , Mihailov , E , Milani , L , Milne , R L , Müller-Nurasyid , M , Nalls , M , Neale , B M , Nevanlinna , H , Neven , P , Newman , A B , Nordestgaard , B G , Olson , J E , Padmanabhan , S , Peterlongo , P , Peters , U , Petersmann , A , Peto , J , Pharoah , P D P , Pirastu , N N , Pirie , A , Pistis , G , Polasek , O , Porteous , D , Psaty , B M , Pylkäs , K , Radice , P , Raffel , L J , Rivadeneira , F , Rudan , I , Rudolph , A , Ruggiero , D , Sala , C F , Sanna , S , Sawyer , E J , Schlessinger , D , Schmidt , M K , Schmidt , F , Schmutzler , R K , Schoemaker , M J , Scott , R A , Seynaeve , C M , Simard , J , Sorice , R , Southey , M C , Stöckl , D , Strauch , K , Swerdlow , A , Taylor , K D , Thorsteinsdottir , U , Toland , A E , Tomlinson , I , Truong , T , Tryggvadottir , L , Turner , S T , Vozzi , D , Wang , Q , Wellons , M , Willemsen , G , Wilson , J F , Winqvist , R , Wolffenbuttel , B H R , Wright , A F , Yannoukakos , D , Zemunik , T , Zheng , W , Zygmunt , M , Bergmann , S , Boomsma , D I , Buring , J E , Ferrucci , L , Montgomery , G W , Gudnason , V , Spector , T D , van Duijn , C M , Alizadeh , BZ , Ciullo , M , Crisponi , L , Easton , D F , Gasparini , P P , Gieger , C , Harris , T B , Hayward , C , Kardia , S L R , Kraft , P , McKnight , B , Metspalu , A , Morrison , A C , Reiner , A P , Ridker , P M , Rotter , J I , Toniolo , D , Uitterlinden , A G , Ulivi , S , Völzke , H , Wareham , N J , Weir , D R , Yerges-Armstrong , L M , Price , A L , Stefansson , K , Visser , J A , Ong , K K , Chang-Claude , J , Murabito , J M M , Perry , J R B & Murray , A 2015 , ' Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair ' , Nature Genetics , vol. 47 , no. 11 , pp. 1294-1303 . https://doi.org/10.1038/ng.3412;
2015