The role of mitochondria in immune-mediated disease: the dangers of a split personality
mitochondria have their own DNA, a 16.5 K closed circle that differs from mammalian DNA in the status of the CpG dinucleotides. Like bacterial DNA, mitochondrial DNA contains unmethylated CpG motifs that allow stimulation of Toll-like (TLR) 9 receptor and likely other internal nucleic acid sensors as well.
| Verfasser: | |
|---|---|
| Dokumenttyp: | Artikel |
| Reihe/Periodikum: | Arthritis research & therapy |
| Verlag/Hrsg.: |
London,
BioMed Central
|
| Sprache: | Englisch |
| ISSN: | 1478-6354 |
| Weitere Identifikatoren: | doi: 10.1186/s13075-016-1063-5 |
| Permalink: | https://search.fid-benelux.de/Record/olc-benelux-1989798128 |
| URL: | NULL NULL |
| Datenquelle: | Online Contents Benelux; Originalkatalog |
| Powered By: | Verbundzentrale des GBV (VZG) |
| Link(s) : | http://dx.doi.org/10.1186/s13075-016-1063-5
http://dx.doi.org/10.1186/s13075-016-1063-5 |
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