Comment to Ruiyu Liu et al.: Comparative analysis of gene expression profiles in normal hip human cartilage and cartilage from patients with necrosis of the femoral head

Ruiyu Liu, * Qi Liu, * Kunzheng Wang, * Xiaoqian Dang and * Feng Zhang We thank Long and colleagues for their interest in our recent publication [1]. We would like to respond to their comments. First, we totally agree with the comment that non-traumatic necrosis of the femoral head (NFH) is a complex disease, mainly caused by excessive steroid use, alcohol drinking, as well as idiopathic NFH without certain etiological factors [5]. Additionally, heavy smoking, overweight, and hyperlipemia were reported to contribute to the development of NFH. To control the potential impacts of steroids, alcoh... Mehr ...