Incidence of malignancy in adult patients with rheumatoid arthritis: a meta-analysis

Patients with rheumatoid arthritis (RA) are at an increased risk of malignancies compared with the general population. This has raised concerns regarding these patients, particularly with the widespread use of immunomodulating therapies, including biologic disease-modifying antirheumatic drugs (DMARDs). We performed a systematic literature review and analysis to quantify the incidence of malignancies in patients with RA and the general population to update previously published data. A literature search was conducted that was consistent with and similar to that in a meta-analysis published in 2... Mehr ...