The effects of experimental knee pain on lower limb corticospinal and motor cortex excitability

Notable weakness of the quadriceps muscles is typically observed as a consequence of knee joint arthritis, knee surgery and knee injury. This is partly due to ongoing neural inhibition that prevents the central nervous system from fully activating the quadriceps, a process known as arthrogenic muscle inhibition (AMI). To investigate the mechanisms underlying AMI, this study explored the effects of experimental knee pain on lower limb corticospinal and motor cortex excitability. Twenty-four healthy volunteers participated in this study. In experiment 1, experimental knee pain was induced by the... Mehr ...