Is urate crystal precipitation a predictor of cardiovascular risk in hyperuricemic patients? A Danish cohort study

There is increasing evidence that both hyperuricemia and gout increase the risk of cardiovascular morbidity and mortality. Whether urate crystal precipitation confers a particular risk above what is already inherent in having hyperuricemia is not well established. We conducted this cohort study to establish whether the presence of monosodium urate crystal precipitation per se is associated with increased risk of cardiovascular diseases among hyperuricemic patients. We identified hyperuricemic individuals who had joint fluid examinations for urate crystals. Individuals with intra-articular urat... Mehr ...