Differential effects on out-of-hospital cardiac arrest of dihydropyridines:real-world data from population-based cohorts across two European countries
AIMS: Various drugs increase the risk of out-of-hospital cardiac arrest (OHCA) in the general population by impacting cardiac ion channels, thereby causing ventricular tachycardia/fibrillation (VT/VF). Dihydropyridines block L-type calcium channels, but their association with OHCA risk is unknown. We aimed to study whether nifedipine and/or amlodipine, often-used dihydropyridines, are associated with increased OHCA risk, and how these drugs impact on cardiac electrophysiology. METHODS AND RESULTS: We conducted a case-control study with VT/VF-documented OHCA cases with presumed cardiac cause fr... Mehr ...
Verfasser: |
Eroglu, Talip E
Mohr, Grimur H
Blom, Marieke T
Verkerk, Arie O
Souverein, Patrick C
Torp-Pedersen, Christian
Folke, Fredrik
Wissenberg, Mads
van den Brink, Lettine
Davis, Richard P
de Boer, Anthonius
Gislason, Gunnar H
Tan, Hanno L |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2020 |
Reihe/Periodikum: |
Eroglu , T E , Mohr , G H , Blom , M T , Verkerk , A O , Souverein , P C , Torp-Pedersen , C , Folke , F , Wissenberg , M , van den Brink , L , Davis , R P , de Boer , A , Gislason , G H , Tan , H L & ESCAPE-NET Investigators 2020 , ' Differential effects on out-of-hospital cardiac arrest of dihydropyridines : real-world data from population-based cohorts across two European countries ' , European heart journal. Cardiovascular pharmacotherapy , vol. 6 , no. 6 , pp. 347–355 . https://doi.org/10.1093/ehjcvp/pvz038 |
Schlagwörter: |
Sudden cardiac arrest
/ Nifedipine
/ Amlodipine
/ Epidemiology
/ out-of-hospital cardiac arrest
/ heart
/ Netherlands
/ Denmark
/ dihydropyridine |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27629975 |
Datenquelle: |
BASE;
Originalkatalog |
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BASE |
Link(s) :
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https://vbn.aau.dk/da/publications/53224e89-1a0c-47d6-8e69-845f9deb3d4c |