Retinal and Cerebral Microvasculopathy:Relationships and Their Genetic Contributions
Purpose: Retinal microvasculopathy may reflect small vessel disease in the brain. Here we test the relationships between retinal vascular parameters and small vessel disease, the influence of cardiovascular risk factors on these relationships, and their common genetic background in a monozygotic twin cohort. Methods: We selected 134 cognitively healthy individuals (67 monozygotic twin pairs) aged ≥60 years from the Netherlands Twin Register for the EMIF-AD PreclinAD study. We measured seven retinal vascular parameters averaged over both eyes using fundus images analyzed with Singapore I Vessel... Mehr ...
Verfasser: |
van de Kreeke, Jacoba A.
Nguyen, H. Ton
Konijnenberg, Elles
Tomassen, Jori
den Braber, Anouk
Ten Kate, Mara
Sudre, Carole H.
Barkhof, Frederik
Boomsma, Dorret I.
Tan, H. Stevie
Verbraak, Frank D.
Visser, Pieter Jelle |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2018 |
Reihe/Periodikum: |
van de Kreeke , J A , Nguyen , H T , Konijnenberg , E , Tomassen , J , den Braber , A , Ten Kate , M , Sudre , C H , Barkhof , F , Boomsma , D I , Tan , H S , Verbraak , F D & Visser , P J 2018 , ' Retinal and Cerebral Microvasculopathy : Relationships and Their Genetic Contributions ' , Investigative ophthalmology & visual science , vol. 59 , no. 12 , pp. 5025-5031 . https://doi.org/10.1167/iovs.18-25341 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27619850 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/3a7f2ab2-116f-4c7a-8509-b93f5dfe9aa3 |